MAK535
Glutathione Reductase Kit
sufficient for 100 colorimetric tests
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About This Item
UNSPSC Code:
12161503
NACRES:
NA.84
Recommended Products
Quality Level
detection method
colorimetric
relevant disease(s)
neurological disorders; cardiovascular diseases; hematological disorder; cancer
shipped in
wet ice
storage temp.
−20°C
General description
Glutathione reductase (GR) reduces oxidized glutathione (GSSG) to the reduced sulfhydryl form GSH which is an important cellular antioxidant. A high GSH/GSSG ratio is important for protection against oxidative stress. Thus, measurement of GR activity is used as indicator for oxidative stress
Features and Benefits
- Linear detection range: 0.4 to 50 U/L
- Compatible with high-throughput handling systems.
Suitability
The kit is suitable for glutathione reductase activity determination in biological samples (e.g. plasma, serum, tissue, and culture media).
Principle
The Glutathione Reductase Kit is designed to accurately measure GR activity in biological samples with a protocol that utilizes Ellman′s method, in which DTNB reacts with the GSH generated from the reduction of GSSG by the GR in a sample to form a yellow product (TNB2-). The rate of change in the optical density, measured at 412 nm, is directly proportional to GR activity in the sample.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Certificates of Analysis (COA)
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