C1138

ι-Carrageenan

commercial grade, Predominantly iota carrageenan

• Synonym(s): Vegetable gelatin
• CAS Number: 9062-07-1
• EC Number: 232-949-3
• MDL number: MFCD00151512
• UNSPSC Code: 12352201
• NACRES: NA.25

Properties

• biological source: algae (Eucheuma spinosum)
• Quality Level: 200
• grade: commercial grade
• form: powder
• color: beige
• useful pH range: 8.0 - 10.5
• solubility: water: soluble ~5 g/L
• storage temp.: room temp
• SMILES string: [S](=O)(=O)([O-])O[C@H]1[C@H](O[C@H]([C@@H]([C@H]1O[C@H]4O[C@H]5[C@@H]([C@H](OC5)[C@H]4O[S](=O)(=O)[O-])O[C@@H]6O[C@@H]([C@@H]([C@@H]([C@H]6O)O)O[S](=O)(=O)[O-])CO)O)O[C@@H]2[C@@H]3OC[C@H]2O[C@@H]([C@@H]3O[S](=O)(=O)[O-])O)CO
• InChI: 1S/C24H38O31S4/c25-1-5-12(52-56(31,32)33)9(27)10(28)22(46-5)49-14-8-4-44-18(14)20(55-59(40,41)42)24(48-8)51-16-11(29)23(47-6(2-26)15(16)53-57(34,35)36)50-13-7-3-43-17(13)19(21(30)45-7)54-58(37,38)39/h5-30H,1-4H2,(H,31,32,33)(H,34,35,36)(H,37,38,39)(H,40,41,42)/p-4/t5-,6-,7-,8-,9-,10-,11-,12+,13+,14+,15+,16-,17+,18+,19-,20-,21+,22+,23+,24-/m1/s1
• InChI key: QIDSWKFAPCTSKL-RRQHLKGPSA-J

Description

General description

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.

Application

Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-,and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.

Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages.[1] As ι-, κ-, and λ-carrageenans have varying degrees of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.[2] ι-Carrageenan may be used to help define the role of carrageenan sulfation levels in physicochemical, biochemical, biological and pharmacological responses.

Preparation Note

Blended from various seaweeds to produce flexible gels.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves