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42052

Sigma-Aldrich

cis-11-Methyl-2-dodecenoic acid

≥90.0% (HPLC)

Synonym(s):

DSF, Diffusible signal factor

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About This Item

Empirical Formula (Hill Notation):
C13H24O2
CAS Number:
677354-23-3
Molecular Weight:
212.33
MDL number:
MFCD09263531
UNSPSC Code:
12352106
PubChem Substance ID:
329756181
NACRES:
NA.25

Quality Level

100

Assay

≥90.0% (HPLC)

storage temp.

−20°C

SMILES string

CC(C)CCCCCCC\C=C/C(O)=O

InChI

1S/C13H24O2/c1-12(2)10-8-6-4-3-5-7-9-11-13(14)15/h9,11-12H,3-8,10H2,1-2H3,(H,14,15)/b11-9-

InChI key

SNTXNGAQYNSTHI-LUAWRHEFSA-N

Application

Diffusible signal factor (cis-11-methyl-2-dodecenoic acid, DSF) is used to study cell-cell communication by pathogenic bacteria such as Xanthomonas campestris pv. Campestris (Xcc). DSF is involved in the synchronization of virulence gene expression and biofilm dispersal.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H315,H319,H411

Precautionary Statements

P273 - P305 + P351 + P338

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

P2645

Protein Kinase A Catalytic Subunit from bovine heart

Bhumika S Shah et al.
PloS one, 13(1), e0191610-e0191610 (2018-01-21)
With new strains of Acinetobacter baumannii undergoing genomic analysis, it has been possible to define regions of genomic plasticity (RGPs), encoding specific adaptive elements. For a selected RGP from a community-derived isolate of A. baumannii, we outline sequences compatible with
Olubukayo-Opeyemi Oyetayo et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 97, 151-157 (2016-11-21)
Solvents used for therapeutic proteins in downstream processing and in formulations often contain stabilizing additives that inhibit denaturation and aggregation. Such additives are mostly selected based on their positive effect on thermal stability of the protein, and are often derived
Sandro Steiner et al.
Toxicology in vitro : an international journal published in association with BIBRA, 38, 150-158 (2016-09-25)
Knowledge of how an in vitro aerosol exposure system delivers a test aerosols to the biological test system is among the most crucial prerequisites for the interpretation of exposure experiments and relies on detailed exposure system characterization. Although various methods
Yaping Yang et al.
Scanning, 38(6), 825-836 (2016-06-30)
Disulfiram (DSF) has been proved to have broad-spectrum anti-alcoholism effects, and it is also found to show stronger anti-tumor effects after chelating with Cu2+ to form DSF-Cu complex. In this work, we studied the anti-tumor activity of DSF-Cu in MCF-7
Ben E Clifton et al.
Nature chemical biology, 14(6), 542-547 (2018-04-25)
The emergence of enzymes through the neofunctionalization of noncatalytic proteins is ultimately responsible for the extraordinary range of biological catalysts observed in nature. Although the evolution of some enzymes from binding proteins can be inferred by homology, we have a
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