A9797

Ambroxol hydrochloride

analytical standard

• Synonym(s): 2-Amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine
• Empirical Formula (Hill Notation): C₁₃H₁₈Br₂N₂O · HCl
• CAS Number: 23828-92-4
• Molecular Weight: 414.56
• EC Number: 245-899-2
• MDL number: MFCD00078932
• UNSPSC Code: 41116107
• PubChem Substance ID: 329771060
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2
• InChI: 1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
• InChI key: QNVKOSLOVOTXKF-PFWPSKEQSA-N

Description

General description

Ambroxol hydrochloride is a mucolytic expectorant and a metabolite of bromhexine. It is used in the treatment of respiratory disorders characterized by viscous or excessive mucus.

Application

Ambroxol hydrochloride standard may be used as a reference standard in the determination of ambroxol hydrochloride in pharmaceutical preparations using reversed-phase sequential injection chromatography (RP-SIC) and reversed-phase high performance liquid chromatography (RP-HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Metabolite of bromhexine.
A Nav1.8-preferring sodium channel blocker

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves