81619

Ectoine

≥95.0% (HPLC)

• Synonym(s): (S)-2-Methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid, Thp(B)
• Empirical Formula (Hill Notation): C₆H₁₀N₂O₂
• CAS Number: 96702-03-3
• Molecular Weight: 142.16
• Beilstein: 7288977
• EC Number: 431-910-1
• MDL number: MFCD03419286
• UNSPSC Code: 24112111
• PubChem Substance ID: 329769212
• NACRES: NA.21

Properties

• Quality Level: 200
• Assay: ≥95.0% (HPLC)
• form: powder
• mol wt: 142.16 g/mol
• storage condition: dry at room temperature
• color: white
• solubility: methanol: soluble 10 mg/mL, clear, colorless to almost colorless
• SMILES string: CC1=N[C@@H](CCN1)C(O)=O
• InChI: 1S/C6H10N2O2/c1-4-7-3-2-5(8-4)6(9)10/h5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
• InChI key: WQXNXVUDBPYKBA-YFKPBYRVSA-N

Description

General description

Ectoine, also known as 4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid, is a zwitterionic amino acid derivative that is a compatible osmoprotectant solute produced in certain aerobic, chemoheterotrophic, and halophilic bacteria to protect against osmotic stress, radiation, and other unfavorable environmental conditions.

Application

The practical applications of ectoine include enzyme stabilization, anti-inflammatory treatment, neurodegenerative disease prevention, and other therapeutic applications.

Biochem/physiol Actions

Ectoine works as an enzyme stabilizer by maintaining hydration and reducing enzyme denaturation due to temperature changes. It also increases the stability of double-stranded DNA at high temperatures.

Other Notes

Stabilizer for enzymes and biological macromolecules

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves