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AB15766

Sigma-Aldrich

Anti-Sox1 Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse, rodent, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NM_005986.2

UniProt accession no.

O00570

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SOX1(6656)

Specificity

Reactivity with other species has not been confirmed.
Recognizes Sox-1, a high mobility group (HMG) transcription factor.

Immunogen

Synthetic peptide from human Sox1.

Application

Anti-Sox1 Antibody detects level of Sox1 & has been published & validated for use in WB, IH.
Research Sub Category
Neuronal & Glial Markers

Developmental Neuroscience
Western blot: 1:200-1:1,000 using ECL. Immunohistochemistry: 1:200-1:1,000. Optimal working dilutions must be determined by the end user.

Linkage

Replaces: AB5768

Physical form

Affinity purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
Format: Purified

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N Mellios et al.
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Rett syndrome (RTT) is an X-linked, neurodevelopmental disorder caused primarily by mutations in the methyl-CpG-binding protein 2 (MECP2) gene, which encodes a multifunctional epigenetic regulator with known links to a wide spectrum of neuropsychiatric disorders. Although postnatal functions of MeCP2
Guided migration of neural stem cells derived from human embryonic stem cells by an electric field.
Feng, JF; Liu, J; Zhang, XZ; Zhang, L; Jiang, JY; Nolta, J; Zhao, M
Stem Cells null
Fabien Almairac et al.
Cancer research, 80(16), 3236-3250 (2020-05-06)
There is great interest in understanding how the cancer stem cell population may be maintained in solid tumors. Here, we show that tumor cells exhibiting stem-like properties and expression of pluripotency markers NANOG and OCT4 can arise from original differentiated
Cells with intense EGFR staining and a high nuclear to cytoplasmic ratio are specific for infiltrative glioma: a useful marker in neuropathological practice.
Burel-Vandenbos, F; Turchi, L; Benchetrit, M; Fontas, E; Pedeutour, Z; Rigau, V; Almairac et al.
Neuro-Oncology null
Ying Pei et al.
Brain research, 1638(Pt A), 57-73 (2015-08-10)
Induced pluripotent stem cells (iPSC) and their differentiated derivatives offer a unique source of human primary cells for toxicity screens. Here, we report on the comparative cytotoxicity of 80 compounds (neurotoxicants, developmental neurotoxicants, and environmental compounds) in iPSC as well
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