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A-046

Supelco

Atropine solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

Atropine solution

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About This Item

Empirical Formula (Hill Notation):
C17H23NO3
CAS Number:
Molecular Weight:
289.37
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®. SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

InChI

1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3

InChI key

RKUNBYITZUJHSG-UHFFFAOYSA-N

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General description

A Certified Spiking Solution® suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from clinical toxicology to forensic analysis and pharmaceutical research. Atropine is a pharmaceutical drug used for treatment of cardiac conditions.

For the analysis of the phytotoxins. Tropane alkaloid.

Application


  • Atropine sulfate solution: Study conducted a systematic review and meta-analysis on the effectiveness of atropine in managing sialorrhea, highlighting its use as a muscarinic antagonist reagent in clinical settings, providing critical insights for pharmacological research atropine applications (Yellepeddi et al., 2024).

  • Pharmacological research atropine: The clinical pharmacokinetics of an atropine oral gel formulation were studied in healthy volunteers, underscoring its importance in acetylcholine receptor studies and its application in developing pharmacokinetic profiles for pharmaceutical research (Parrot et al., 2024).

  • Atropine as a muscarinic antagonist in pharmacological research: The study discussed the utility of plant alkaloids, including atropine, in treating eye diseases, illustrating atropine′s role as a vital ophthalmic research chemical and its broader implications in medical research (Lorrai et al., 2024).

  • High purity atropine solution for biochemical studies: The study developed a new method for solvent suppression in pure shift NMR, enhancing the understanding of atropine′s interactions at the molecular level, which is crucial for advancing analytical standards for delta8-THC and related compounds in scientific research (Gates et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marija Lukac et al.
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 23(1), 80-84 (2013-02-05)
Evaluation of the effectiveness of oral atropine versus surgical therapy for hypertrophic pyloric stenosis (HPS). A total of 66 consecutive patients with HPS were treated at the University Children's Hospital between January 2006 and December 2011. The diagnosis was initially
Yu-Wen Cheng et al.
International journal of medicinal mushrooms, 15(3), 277-286 (2013-05-15)
In our previous research, Cordyceps militaris (CM) had a hypoglycemic effect in normal rats. In this study we wanted to elucidate whether CM also had an effect on diabetic rats. Twelve rats with streptozotocin-induced diabetes were separated randomly into 2
A I Strelnikova et al.
Bulletin of experimental biology and medicine, 154(2), 180-183 (2013-01-19)
Acetylcholine (5.5×10(-10)-5.5×10(-6)M) accelerated erythrocyte agglutination in men, non-pregnant women in follicular phase of the menstrual cycle, and pregnant women in the first trimester. The effect was blocked with atropine (5.5×10(-6)M). Acetylcholine had no effect on the rate of erythrocyte agglutination
Yoshizumi Takemura et al.
American journal of physiology. Lung cellular and molecular physiology, 304(6), L428-L437 (2013-01-08)
We and others have shown that epithelial Na(+) channels (ENaC) in alveolar type 2 (AT2) cells are activated by β2 agonists, steroid hormones, elevated oxygen tension, and by dopamine. Although acetylcholine receptors (AChRs) have been previously described in the lung
F Aura Kullmann et al.
Life sciences, 92(12), 733-739 (2013-02-13)
To determine if the muscarinic agonist, bethanechol, inhibits the non-cholinergic, atropine-resistant (i.e. putatively purinergic) component of naturally occurring (i.e. reflexogenic) bladder contractions in vivo in the rat, as previously described in vitro. Our second aim was to determine if elevation

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