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Key Documents

800812P

Avanti

12:0 DG

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-didodecanoyl-sn-glycerol; DG(12:0/12:0/0:0); 110611

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About This Item

Empirical Formula (Hill Notation):
C27H52O5
CAS Number:
60562-15-4
Molecular Weight:
456.70
UNSPSC Code:
12352211
NACRES:
NA.25

description

1,2-dilauroyl-sn-glycerol

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (800812P-10mg)
pkg of 1 × 200 mg (800812P-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

neutral glycerides
neutral lipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C27H52O5/c1-3-5-7-9-11-13-15-17-19-21-26(29)31-24-25(23-28)32-27(30)22-20-18-16-14-12-10-8-6-4-2/h25,28H,3-24H2,1-2H3/t25-/m0/s1

InChI key

OQQOAWVKVDAJOI-VWLOTQADSA-N

General description

sn-1,2-diacylglycerols comprise short saturated acyl side chains (C4-C10) and 12:0 DG is also called 1,2-dilauroyl-sn-glycerol.

Application

12:0 DG has been used as an internal standard for spiking serum samples for liquid chromatography–mass spectrometry analysis. It may be used as an internal standard for spiking RAW 264.7 cells for mass spectroscopy studies and in reverse phase liquid chromatography coupled mass spectrometer for lipidomics studies of human plasma and serum samples.

Biochem/physiol Actions

1,2-dilauroyl-sn-glycerol is a polymerization initiator used in the synthesis of (R)-3-((2-bromo-2-methylpropanoyl)oxy)propane-1,2-diyl didodecanoate (BMPD). sn-1,2-diacylglycerols are prime regulators of biological functions especially in platelets. They also activate protein kinase C.

Packaging

5 mL Amber Glass Screw Cap Vial (800812P-10mg)
5 mL Amber Glass Screw Cap Vial (800812P-200mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Structural Properties of 1, 2-Diacyl-sn-glycerol in Bulk and at the Water Interface by Molecular Dynamics
van Buuren AR, et al.
Langmuir, 11(8), 2957-2965 (1995)
Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm
Callender HL, et al.
Analytical Chemistry, 79(1), 263-272 (2007)
Lipidated polymers for the stabilization of cubosomes: nanostructured drug delivery vehicles
Grace JL, et al.
Chemical Communications (Cambridge, England), 53(76), 10552-10555 (2017)
Lipid Profile Characterization and Lipoprotein Comparison of Extracellular Vesicles from Human Plasma and Serum
Sun Y, et al.
Metabolites, 9(11), 259-259 (2019)
Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation
Ebeling JG, et al.
Proceedings of the National Academy of Sciences of the USA, 82(3), 815-819 (1985)
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