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D131806

Sigma-Aldrich

3,4-Dimethoxybenzoic acid

≥99%

Synonym(s):

Veratric acid, 3,4-Dimethoxybenzoic acid

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About This Item

Linear Formula:
(CH3O)2C6H3CO2H
CAS Number:
Molecular Weight:
182.17
Beilstein:
518285
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

≥99%

form

powder

mp

179-182 °C (lit.)

SMILES string

COc1ccc(cc1OC)C(O)=O

InChI

1S/C9H10O4/c1-12-7-4-3-6(9(10)11)5-8(7)13-2/h3-5H,1-2H3,(H,10,11)

InChI key

DAUAQNGYDSHRET-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R G Dickinson et al.
Journal of pharmaceutical sciences, 80(10), 952-957 (1991-10-01)
The HPLC methods for the determination of plasma concentrations of the antispasmodic agent mebeverine (0.01-10 micrograms/mL) and its hydrolysis product veratric acid (0.1-50 micrograms/mL) are presented. Mebeverine was demonstrated to hydrolyze readily in fresh unbuffered human and rat plasma samples
Marta Czarnecka et al.
Molecules (Basel, Switzerland), 23(8) (2018-08-15)
Phenolic acids and its methoxy derivatives are known to induce caspase-mediated apoptosis activity and exhibit cytotoxic effect towards various cancer cell lines. However, their low stability and poor bioavailability in the human organism extensively restrict the utility of this group
Murugesan Saravanakumar et al.
European journal of pharmacology, 671(1-3), 87-94 (2011-09-23)
The present study was undertaken to assess the antihypertensive and antioxidant effects of veratric acid on N(ω)-nitro-L arginine methyl ester (L-NAME) induced hypertensive rats. Hypertension was induced in adult male albino rats of the Wistar strain, weighing 180-220 g, by
Anna Drzazga et al.
Nutrients, 12(4) (2020-04-26)
Diabetes mellitus is a worldwide health problem with high rates of mortality and morbidity. Management of diabetes mellitus by dietary components is achievable especially at the initial stage of the disease. Several studies confirmed the antidiabetic activities of simple phenolic
Murugesan Saravanakumar et al.
Journal of cardiovascular pharmacology, 59(6), 553-562 (2012-03-01)
Hypertension is associated with dyslipidemia, which is a significant risk factor for cardiovascular complications. This study was undertaken to investigate the effects of veratric acid (VA) on blood pressure, plasma, and tissue lipid profile in N-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive

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