C65408
2-(4-Chlorophenyl)ethylamine
98%
Synonym(s):
4-Chlorophenethylamine
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About This Item
Linear Formula:
ClC6H4CH2CH2NH2
CAS Number:
Molecular Weight:
155.62
Beilstein:
508247
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
Assay
98%
form
liquid
refractive index
n20/D 1.548 (lit.)
bp
60-65 °C/0.1 mmHg (lit.)
density
1.112 g/mL at 25 °C (lit.)
SMILES string
NCCc1ccc(Cl)cc1
InChI
1S/C8H10ClN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2
InChI key
SRXFXCKTIGELTI-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
222.8 °F - closed cup
Flash Point(C)
106 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Francisco Martínez-Cruz et al.
Neuroscience letters, 392(1-2), 1-4 (2005-11-29)
Abnormal oxidative stress was observed in hyperphenylalaninemia and other inborn errors of intermediary metabolism, owing to the accumulation of toxic metabolites, free radical production and increased LPO products. In our model of maternal hyperphenylalaninemia, pregnant rats were injected with 300
Giulia Guiducci et al.
Nucleic acids research, 47(8), 4240-4254 (2019-02-28)
Enzymes of intermediary metabolism are often reported to have moonlighting functions as RNA-binding proteins and have regulatory roles beyond their primary activities. Human serine hydroxymethyltransferase (SHMT) is essential for the one-carbon metabolism, which sustains growth and proliferation in normal and
Khalid Touiki et al.
Psychopharmacology, 182(4), 562-569 (2005-09-01)
Harmane and norharmane (two beta-carbolines) are tobacco components or products. The effects of harmane and norharmane on serotonergic raphe neurons remain unknown. Harmane and norharmane are inhibitors of the monoamine oxidases A (MAO-A) and B (MAO-B), respectively. To study the
Marina Marani et al.
Oncotarget, 7(4), 4570-4583 (2015-12-31)
Serine hydroxymethyltransferase (SHMT) is a central enzyme in the metabolic reprogramming of cancer cells, providing activated one-carbon units in the serine-glycine one-carbon metabolism. Previous studies demonstrated that the cytoplasmic isoform of SHMT (SHMT1) plays a relevant role in lung cancer.
G B Baker et al.
Progress in neuro-psychopharmacology & biological psychiatry, 6(4-6), 343-346 (1982-01-01)
1. The accumulation of p-chlorophenylethylamine (pCPE) in rat brain after administration of pargyline plus p-chlorophenylalanine (pCPA) is demonstrated. 2. Measurements of pCPE in brain were performed at 0.25 h, 1 h and 4 h after administration of pCPA to pargyline-pretreated
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