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337951

Sigma-Aldrich

Quercetin hydrate

≥95%

Synonym(s):

2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one hydrate

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About This Item

Empirical Formula (Hill Notation):
C15H10O7 · xH2O
CAS Number:
849061-97-8
Molecular Weight:
302.24 (anhydrous basis)
EC Number:
204-187-1
MDL number:
MFCD03847906
UNSPSC Code:
12352100
PubChem Substance ID:
24860506
NACRES:
NA.22

Assay

≥95%

solubility

DMSO: slightly soluble

SMILES string

[H]O[H].Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,16-19,21H;1H2

InChI key

OKXFBEYCJRMINR-UHFFFAOYSA-N

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General description

Quercetin is an antitrypanosomal and antileishmanial compound. Quercetin is a well-known bioflavonoid and its influence on tumour growth in vivo has been reported. Quercetic exhibits leishmanicidal effect on the amastigote stage of Leishmania donovani.

Application

Quercetin hydrate was used as leishmanicidal flavonol to investigate the inhibition of recombinant arginase from Leishmania amazonensis by quercetin, quercitrin and isoquercitrin.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hua Chen et al.
Food chemistry, 221, 248-257 (2016-12-17)
The study examined the capability of phytoglycogen (PG) to improve the water solubility of quercetin (QC). PG-QC formulations were prepared by mixing a QC ethanol solution with a PG aqueous solution followed with vacuum drying of the supernatant. PG-QC formulations
Shengfeng Peng et al.
Journal of agricultural and food chemistry, 67(26), 7506-7511 (2019-06-12)
The poor water solubility and oral bioavailability of many lipophilic polyphenols can be improved through the use of colloidal delivery systems. In this study, a pH-driven method was used to encapsulate curcumin, quercetin, and resveratrol within nanoliposomes. This method is
Azar Kajbafvala et al.
Pharmaceutical development and technology, 23(8), 741-750 (2016-11-23)
The aim of this study was to develop a new microemulsion formulation for topical application of poorly soluble drug named quercetin. In order to design suitable microemulsion system, the pseudo-ternary phase diagrams of microemulsion systems were constructed at different surfactant/co-surfactant
Shimaa M A Sayed et al.
Frontiers in pharmacology, 12, 604435-604435 (2021-02-27)
To uncover potential anti-aging capacities of Traditional Chinese Medicine (TCM), the nematode Caenorhabditis elegans was used to investigate the effects of Eucommia ulmoides and Cuscuta chinensis extracts, selected by screening seven TCM extracts, on different healthspan parameters. Nematodes exposed to
Tumour response to quercetin, a bioflavonoid with some promises in therapies.
Indap MA, et al.
Indian Journal of Pharmaceutical Sciences, 68(5), 570-570 (2006)
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