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292206

Sigma-Aldrich

2-Methyl-1,3-dioxolane

97%

Synonym(s):

Acetaldehyde ethylene acetal

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About This Item

Empirical Formula (Hill Notation):
C4H8O2
CAS Number:
Molecular Weight:
88.11
Beilstein:
102520
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

refractive index

n20/D 1.398 (lit.)

bp

82-83 °C (lit.)

density

0.982 g/mL at 25 °C (lit.)

functional group

ether

SMILES string

CC1OCCO1

InChI

1S/C4H8O2/c1-4-5-2-3-6-4/h4H,2-3H2,1H3

InChI key

HTWIZMNMTWYQRN-UHFFFAOYSA-N

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General description

The kinetics and mechanism of the gas-phase thermal decomposition of 2-methyl-1,3-dioxolane has been studied in a static system. The infrared spectra of solid, liquid and gaseous 2-methyl-1,3-dioxolane has been studied. Low-temperature ozonation of 2-methyl-1,3-dioxolane in acetone-d6, methyl acetate and tert-butyl methyl ether has been reported.

Pictograms

Flame

Signal Word

Danger

Hazard Statements

Hazard Classifications

Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

28.4 °F - closed cup

Flash Point(C)

-2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R A Huff et al.
Journal of neurochemistry, 62(1), 388-391 (1994-01-01)
cis-Methyldioxolane (CD) is a muscarinic receptor agonist. [3H]CD has been used to label a subpopulation of muscarinic receptors described as exhibiting high agonist affinity. Pharmacological evidence suggests that the population of receptors labeled by [3H]CD consists of m2 and/or m4
E T Iwamoto et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 329-338 (1993-07-01)
The present study was designed to characterize the antinociception produced by the administration of a potent muscarinic agonist into the intrathecal space of the lumbar spinal cord of male Sprague-Dawley rats. Seven days after surgical implantation of intrathecal catheters, animals
Spectra and structure of small ring compounds. XXXVI. 2-methyl-1, 3-dioxolane; 2-methyl-1, 3-dioxolane-d4; 2-methyltetrahydrofuran; and methylcyclopentane.
Durig JR, et al.
Journal of Raman Spectroscopy, 1(1), 17-45 (1973)
M Watson et al.
Brain research, 346(2), 387-391 (1985-11-04)
The relationship of choline acetyltransferase (ChAT) activity and high affinity binding of the potent and selective sodium-dependent choline uptake inhibitor [3H]hemicholinium-3 ([3H]HC-3) to high-affinity binding of the muscarinic agonist [3H](+)-cis-methyldioxolane ([3H](+)CD), the putative M1 selective antagonist [3H]pirenzepine ([3H]PZ) and the
T W Vickroy et al.
The Journal of pharmacology and experimental therapeutics, 229(3), 747-755 (1984-06-01)
The high-affinity agonist binding state of muscarinic receptors in the rat heart and cerebral cortex has been pharmacologically characterized in parallel studies. Muscarinic sites were labeled and studied with the aid of a highly specific, rapid filtration binding assay using

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