1044516

Atorvastatin Calcium

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Atorvastatin hemicalcium salt sesquihydrate
• Empirical Formula (Hill Notation): C₆₆H₆₈CaF₂N₄O₁₀ · 3H₂O
• CAS Number: 344423-98-9
• Molecular Weight: 1209.39
• MDL number: MFCD09752074
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: atorvastatin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• SMILES string: [Ca+2].Fc5ccc(cc5)c6[n](c(c(c6c8ccccc8)C(=O)Nc7ccccc7)C(C)C)CC[C@@H](O)C[C@@H](O)CC(=O)O.Fc1ccc(cc1)c2[n](c(c(c2c4ccccc4)\C(=N\c3ccccc3)\[O-])C(C)C)CC[C@@H](O)C[C@@H](O)CC(=O)[O-].O.O.O
• InChI: 1S/2C33H35FN2O5.Ca.3H2O/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);;3*1H2/q;;+2;;;/p-2/t2*26-,27-;;;;/m11..../s1
• InChI key: SHZPNDRIDUBNMH-NIJVSVLQSA-L

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Atorvastatin Calcium is a synthetic selective inhibitor of HMG-CoA reductase. It is insoluble in aqueous solution with pH below 4 and is freely soluble in methanol.

Application

Atorvastatin calcium USP reference standard intended for use in specified quality tests and assays.

Also used to prepare system suitability, standard, system suitability stock, identification, and standard stock solution for assay and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):

• Atorvastatin Calcium
• Atorvastatin Calcium Tablets
• Amlodipine and Atorvastatin Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• Target Organs: Liver
• Pictograms: GHS08,GHS09
• Signal Word: Warning
• Hazard Codes: H373,H411
• Precautionary Statements: P260 - P273 - P314 - P391 - P501
• Hazard Classifications: Aquatic Chronic 2 - STOT RE 2
• Storage Class: 11 - Combustible Solids