SAB4501597

Anti-JAK1 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): JAK-1, JAK1, JAK1A, Janus kinase 1, kinase Jak1
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 131 kDa
• species reactivity: human, mouse, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P23458
• UniProt accession no.: P23458
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... JAK1(3716)

Description

General description

Anti-JAK1 Antibody detects endogenous levels of total JAK1 protein.

Janus kinase 1 (JAK1) is a non-receptor tyrosine kinase, that belongs to the JAK family. It is located on human chromosome 1p31.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human JAK1.

Immunogen Range: 988-1037

Biochem/physiol Actions

Mutations in janus kinase 1 (JAK1) results in leukemia, breast cancer, lung cancer and HCC (hepatocellular carcinoma). It participates in signaling with many cytokines. JAK1 is also involved in the immune response and the initiation of allergic airway disease.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable