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S3547

Sigma-Aldrich

Sesame oil

Sesame oil

Antioxidant, delivery vehicle for fat-soluble compounds

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About This Item

CAS Number:
8008-74-0
EC Number:
232-370-6
MDL number:
MFCD00132243
UNSPSC Code:
12352211
NACRES:
NA.25
Pricing and availability is not currently available.

biological source

Sesamum indicum (sesame)

Quality Level

100

form

liquid

density

0.92 g/mL at 25 °C

functional group

oleic acid

lipid type

oils

shipped in

ambient

storage temp.

room temp

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General description

Sesame oil may be used in the production of biodiesel and may serve as a viable alternative for the diesel fuel.[1] It acts as an antioxidant having neuroprotective activity on brain hippocampus of rat in focal cerebral ischemia, when given as a dietary supplement.[2] Consumption of sesame oil has a beneficial effect on blood glucose, glycosylated hemoglobin, lipid peroxidation, and antioxidant levels in diabetic rats.[3]

Application

Sesame oil is suitable:
  • for dissolving free testosterone[4]
  • for the preparation of tamoxifen i.p. injection[5]
  • for dissolving aromatizable androgen testosterone and non-aromatizable androgen 5α-dihydrotestosterone[6]
  • as a delivery vehicle for the injection of estradiol benzoate[7]
  • for dissolving progesterone and estradiol-17β[8]
  • for dissolving semisynthetic form of acetyl-11-keto-β-boswellic acid[9]
Used in research applications as delivery vehicle for fat-soluble compounds including steroidal hormones and toxins. Sesame oil has antioxidant properties and was shown to protect against lipopolysaccharide (LPS)-stimulated oxidative stress in animal models.

Storage Class Code

10 - Combustible liquids

WGK

awg

Flash Point(F)

491.0 °F

Flash Point(C)

255 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000376809
0000376809
0000256527
0000220211
0000256527

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Saif Ahmad et al.
Life sciences, 79(20), 1921-1928 (2006-07-11)
Oxidative stress may be regarded as an imbalance between free radical production and opposing antioxidant defenses. Free radical oxidative stress is implicated in rat cerebral ischemia and naturaceutical antioxidants are dietary supplements that have been reported to have neuroprotective activity.
Abdurrahman Saydut et al.
Bioresource technology, 99(14), 6656-6660 (2008-01-08)
The sesame (Sesamum indicum L.) oil was extracted from the seeds of the sesame that grows in Diyarbakir, SE Anatolia of Turkey. Sesame seed oil was obtained in 58wt/wt%, by traditional solvent extraction. The methylester of sesame (Sesamum indicum L.)
Martin Höhne et al.
The American journal of pathology, 182(2), 332-338 (2012-12-19)
Podocytes, the visceral epithelial cells of the kidney glomerulus, elaborate primary and interdigitating secondary extensions to enwrap the glomerular capillaries. A hallmark of podocyte injury is the loss of unique ultrastructure and simplification of the cell shape, called foot process
C Anthoni et al.
American journal of physiology. Gastrointestinal and liver physiology, 290(6), G1131-G1137 (2006-01-21)
Recent clinical trials of the gum resin of Boswellia serrata have shown promising results in patients with ulcerative colitis. The objective of this study was to determine whether a semisynthetic form of acetyl-11-keto-beta-boswellic acid (sAKBA), the most potent anti-inflammatory component
Justin T Hsieh et al.
Neuroendocrinology, 103(5), 518-530 (2015-09-12)
Preclinical evidence suggests that progesterone improves recovery after intracerebral hemorrhage (ICH); however, gonadal hormones have sex-specific effects. Therefore, an experimental model of ICH was used to assess recovery after progesterone administration in male and female rats. ICH was induced in
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. E' un prodotto iniettabile per utilizzo in prodotti galenici a lento rilascio?

    1 answer

    1. This product is used in research applications as a delivery vehicle for fat-soluble compounds including steroidal hormones and toxins. That said, it is not QC tested in an injectable format on animals or humans (though many researchers do use research-grade products with animals) so its use in that manner cannot be guaranteed. The literature articles on the product page do not mention its use in slow-release galenic products, so this is something the end user would need to determine.

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Reviews

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    • Review 1
    • Vote 1
    5 out of 5 stars.

    Sesame oil for research

    Reasonably priced and qualify product. Good place go buy scientific sesame oil

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