Key Documents

View All Documentation

Diethylumbelliferyl phosphate

Name: Diethylumbelliferyl phosphate
Brand: SIGMA

≥98% (HPLC), cholesterol esterase inhibitor, oil

Synonym(s):

DEUP, UBP

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₇O₆P

CAS Number:

897-83-6

Molecular Weight:

312.25

UNSPSC Code:

12352200

PubChem Substance ID:

24894155

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

oil

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Diethylumbelliferyl phosphate, ≥98% (HPLC), oil

Quality Segment

100

assay

≥98% (HPLC)

form

oil

color

colorless to yellow

solubility

DMSO: >5 mg/mL

storage temp.

−20°C

SMILES string

CCOP(=O)(OCC)Oc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C14H17O6P/c1-4-17-21(16,18-5-2)20-11-6-7-12-10(3)8-14(15)19-13(12)9-11/h6-9H,4-5H2,1-3H3

InChI key

GHGRYKAFUNNHBG-UHFFFAOYSA-N

Description

Application

Diethylumbelliferyl phosphate has been used as a lipase inhibitor to treat wild-type myeloblasts for in vitro neutrophil differentiation assays.

Biochem/physiol Actions

Diethylumbelliferyl phosphate (DEUP), an organophosphate does not block protein kinase activity A in vitro.[1]

Diethylumbelliferyl phosphate is a selective, potent cholesterol esterase inhibitor. It blocks steroidogenesis primarily by preventing cholesterol transport into the mitochondria of steroidogenic cells. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. IC₅₀ = 11.6 μM.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	M7945	G5048	670105
Sigma-Aldrich D7692 Diethylumbelliferyl phosphate	Sigma-Aldrich M7945 Mephetyl tetrazole	Sigma-Aldrich G5048 Geranylgeranylacetone	Millipore 670105 UDP-α-D-N-Acetylgalactosamine, Disodium Salt
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥97% (HPLC)
form oil	form oil	form oil	form solid
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. −20°C
solubility DMSO: >5 mg/mL	solubility DMSO: >5 mg/mL	solubility DMSO: >5 mg/mL	solubility water: 50 mg/mL
color colorless to yellow	color pale yellow	color clear	color white

pictograms

GHS06

signalword

Danger

hcodes

H300

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.