B4558

BW B70C

>98% (HPLC), solid

• Synonym(s): N-[3-[3-4(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea
• Empirical Formula (Hill Notation): C₁₇H₁₇FN₂O₃
• CAS Number: 134470-38-5
• Molecular Weight: 316.33
• NACRES: NA.77
• PubChem Substance ID: 24278269
• UNSPSC Code: 51111800
• MDL number: MFCD00890868
• Assay: >98% (HPLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: >98% (HPLC)
• form: solid
• color: white
• solubility: DMSO: soluble 22 mg/mL
• storage temp.: 2-8°C
• SMILES string: CC(\C=C\c1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O
• InChI: 1S/C17H17FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-12,22H,1H3,(H2,19,21)/b6-5+
• InChI key: UAIYNMRLUHHRMF-AATRIKPKSA-N
• Gene Information: human ... ALOX5AP(241)

Description

Application

BW B70C has been used as a 5-lipoxygenase inhibitor to study its effects on eryptosis in erythrocytes.

Biochem/physiol Actions

BW B70C exhibits anti-inflammatory and anti-tumorigenic activities. It exhibits therapeutic effects against hepatocellular carcinoma. BW B70C plays a role in allergen-induced bronchoconstriction by reducing the allergic airway closure and glycoconjugate secretion.

Selective 5-lipoxygenase inhibitor.

Safety Information

• Storage Class: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)