AB1834P
Anti-Monocyte Chemotactic Protein-1 Antibody
Chemicon®, from rabbit
Synonym(s):
MCP-1, MCAF, CCL2
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
neutralization: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CCL2(6347)
Related Categories
Specificity
Reacts with rat MCP-1
Immunogen
Highly pure (>98%) recombinant rat MCP-1
Application
Anti-Monocyte Chemotactic Protein-1 Antibody is an antibody against Monocyte Chemotactic Protein-1 for use in ELISA, WB, NEUT.
ELISA: To detect rat MCP-1 (MCAF) by direct ELISA (using 100 μL/well antibody solution) a concentration of at lease 0.5 μg/mL of this antibody is required. Should allow detection of 0.2 - 0.4 ng/well of recombinant rat MCP-1 (MCAF).
Western blot: 0.1 - 0.2 μg/mL, this dilution should offer a detection limit of 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of rat MCP-1 (100 ng/mL), a concentration of 4.0-6.0 μg/mL of this antibody is required.
Optimal working dilutions must be determined by the end user.
Western blot: 0.1 - 0.2 μg/mL, this dilution should offer a detection limit of 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of rat MCP-1 (100 ng/mL), a concentration of 4.0-6.0 μg/mL of this antibody is required.
Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Cytokines & Cytokine Receptors
Physical form
Affinity purified immunoglobulin. Lyophilized from 0.5X PBS pH 7.4. Contains no preservative. Reconstitute with sterile distilled water to 0.1 - 1.0 mg/ml.
Storage and Stability
Maintain lyophilized material desiccated at 2°-8°:C for up to 12 months from date of receipt. After reconstitution maintain at -20°C in convenient undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus.
Russo, LA; Peano, BJ; Trivedi, SP; Cavalcanto, TD; Olenchock, BA; Caruso, JA; Smolock et al.
Reproductive Biology and Endocrinology null
Erhong Zhang et al.
American journal of reproductive immunology (New York, N.Y. : 1989), 74(5), 457-466 (2015-08-20)
Male obesity has been linked to subfecundity. This study is to investigate the effects of GLP-1 receptor (GLP-1R) agonist exenatide on sperm quality in high-fat diet (HFD)-induced obese mice. After 12 weeks of chow diet (CD) or HFD challenge, mice
Marie-Elsa Brochu et al.
Journal of neuroinflammation, 8, 55-55 (2011-05-24)
Preterm and term newborns are at high risk of brain damage as well as subsequent cerebral palsy and learning disabilities. Indeed, hypoxia-ischemia (HI), pathogen exposures, and associated intracerebral increase of pro-inflammatory cytokines have all been linked to perinatal brain damage.
Clémence Guiraut et al.
International journal of molecular sciences, 17(12) (2016-11-30)
The medium-size intra-cranial arteries arising from the carotid bifurcation are prone to perinatal arterial ischemic strokes (PAIS). PAIS' physiopathology needs to be better understood to develop preventive and therapeutic interventions that are currently missing. We hypothesized that materno-fetal inflammation leads
Laongdao Thongnak et al.
Journal of biochemical and molecular toxicology, 36(4), e22978-e22978 (2021-12-24)
Long-term use of a high-fat diet with high-fructose (HFF) intake could promote insulin resistance and induce lipid accumulation leading to kidney injury possibly via impairment of the autophagy process and enhancement of the inflammasome pathway. We investigated whether dapagliflozin as
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service