280135

2-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide

Dye content 95 %

• Synonym(s): 2-Di-1-ASP
• Empirical Formula (Hill Notation): C₁₆H₁₉IN₂
• CAS Number: 2156-29-8
• Molecular Weight: 366.24
• Beilstein: 3776369
• EC Number: 218-460-8
• MDL number: MFCD00011980
• UNSPSC Code: 12352103
• PubChem Substance ID: 57648287
• NACRES: NA.23

Properties

• form: solid
• composition: Dye content, 95%
• mp: 280 °C (dec.) (lit.)
• λmax: 466 nm
• fluorescence: λ_ex 466 nm; λ_em 504 nm in methanol; λ_ex 475 nm; λ_em 589 nm in methanol
• SMILES string: [I-].CN(C)c1ccc(cc1)\C=C\c2cccc[n+]2C
• InChI: 1S/C16H19N2.HI/c1-17(2)15-10-7-14(8-11-15)9-12-16-6-4-5-13-18(16)3;/h4-13H,1-3H3;1H/q+1;/p-1
• InChI key: XPOIQAIBZGSIDD-UHFFFAOYSA-M

Description

General description

2-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide (DASPMI) is a mitochondria staining styryl dye that is used to generate a quick responsive mechanism by applying changes in transmembrane potential. DASPMI can be used as a low toxic stain that shows a fluorescent behavior for mitochondria.

2-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide (DASPMI) is a styrylcyanine dye.

Application

DASPMI is a polar sensitive dye that measures the membrane potential of mitochondria in living cells. It may be used as a light absorber in the development of a photoinitiator based system.

DASPMI is popularly used in selective staining of mitochondria in living cells.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves