Passa al contenuto
Merck

Novel inhibitors of poly(ADP-ribose) synthetase.

The Biochemical journal (1980-03-01)
M R Purnell, W J Whish
ABSTRACT

In a search for new inhibitors of the nuclear enzyme poly(ADP-ribose) synthetase, it was found that various benzamides substituted in the 3-position were the most inhibitory compounds found to date. Two of the benzamides, 3-aminobenzamide and 3-methoxybenzamide, were found to be competitive inhibitors, with Ki values or less than 2 microM.

MATERIALI
N° Catalogo
Marchio
Descrizione del prodotto

Sigma-Aldrich
3-Aminobenzamide, ≥99% (TLC)
Sigma-Aldrich
3-Nitrobenzamide, 98%