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Synthesis of fluorinated 1-(3-morpholin-4-yl-phenyl)-ethylamines.

Bioorganic & medicinal chemistry letters (2003-05-06)
Yong-Jin Wu, Huan He, Li-Qiang Sun, Dedong Wu, Qi Gao, Hui-Yin Li
ABSTRACT

The synthesis of four (+/-)-fluorinated 1-(3-morpholin-4-yl-phenyl)-ethylamines and an enantioselective approach to these amines through reductive amination are described.