Highly enantioselective synthesis of isoxazoline N-oxides.

Highly enantioselective synthesis of isoxazoline N-oxides.

Chemical communications (Cambridge, England) (2008-05-16)

Chun-Yin Zhu, Xian-Ming Deng, Xiu-Li Sun, Jun-Cheng Zheng, Yong Tang

ABSTRACT

The reaction of cinchonidine (cinchonine)-derived ammonium salts with nitroolefins in the presence of Cs2CO3 to afford optically active isoxazoline N-oxides with excellent ee and high de values has been developed.

MATERIALI

N° Catalogo

Marchio

Descrizione del prodotto

C80407

Sigma-Aldrich

Cinchonidine, 96%