The supplier has provided the following information: store the powder at -20°C and dissolve it in sterile water, typically at 20 mg/ml. The solution may appear slightly hazy. It is recommended to store the solution in aliquots at -80°C, but -20°C is suitable for a short period of time, although the supplier does not define what is meant by a 'short period'. It is advised to avoid repeated freezing and thawing cycles, and the supplier suggests aliquoting the product once in solution.
V2501
Snake venom from Vipera russelli (Russell′s Viper)
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About This Item
Codice UNSPSC:
12352202
Prezzi e disponibilità al momento non sono disponibili
Prodotti consigliati
Temperatura di conservazione
−20°C
Livello qualitativo
Applicazioni
Snake venom from Vipera russelli (Russell′s Viper) has also been used as a positive control in indirect and sandwich enzyme-linked immunosorbent assay (ELISA) to study the performance of the immunochromatographic test (ICT)-Viper in venom detection in vitro and the detection of clinical envenoming, respectively.[1]
Snake venom from Vipera russelli (Russell′s Viper) has been used for extraction of coagulant protein for complex generation with bovine X factor.[2]
Azioni biochim/fisiol
Snake venom can impose death on humans and animals.[3] Nevertheless, snake venom also exhibits anti-bacterial and wound healing properties.[4] Therefore, it is used as a therapeutic for treating various diseases including thrombosis, arthritis, and cancer.[3]
Snake venom from Russell′s Viper is rich in toxins and proteinase inhibitors.[5] The receptor from Vipera russelli β-RTX, interacts with monoamines and opiate and prevents their interaction with native receptors.[6] The proteases from Russell′s Viper mediate coagulation in human plasma.[7] The neurotoxicity of the venom is contributed by phospholipases.[8]
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Certificati d'analisi (COA)
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Snake Venom Proteinase Inhibitors: II. Chemical Structure of Inhibitor II Isolated from the Venom of Russell's viper (Vipera russelli)
TAKAHASHI H, et al.
Journal of Biochemistry, 76(4), 721-733 (1974)
Coagulation factor X activating enzyme from Russell's viper venom (RVV-X). A novel metalloproteinase with disintegrin (platelet aggregation inhibitor)-like and C-type lectin-like domains.
Takeya H, et al.
The Journal of Biological Chemistry, 267(20), 14109-14117 (1992)
Interaction of lanthanide ions with bovine factor X and their use in the affinity chromatography of the venom coagulant protein of Vipera russelli.
Furie BC and Furie B
The Journal of Biological Chemistry, 250(2), 601-608 (1975)
Sanjoy Kumar Pal et al.
Indian journal of experimental biology, 40(12), 1353-1358 (2003-09-17)
Snake bite injuries and death are socio-medical problems of considerable magnitude. In India a large number of people suffer and die every year due to snake venom poisoning. Snake venom, though greatly feared, is a natural biological resource, containing several
Snake venom proteins: development into antimicrobial and wound healing agents
PerumalSamy R, et al.
Mini-Reviews in Organic Chemistry, 11(1), 4-14 (2014)
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How can V2501 be diluted? Where can I find the documentation for this process?
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Origin of venom RVV, do you issue Cites certificate?
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See the link below to review a sample Certificate of Origin for this product:
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COO/Q12/V2501-100MGSLCL9857.pdfThese documents are lot-specific and may be supplied by our Technical Service team. We kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Documentation" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.
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