T2402
Anti-Mouse IgG (whole molecule)−TRITC antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
Sinonimo/i:
Rabbit Anti-Mouse IgG (whole molecule)−Tetramethylrhodamine isothiocyanate
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About This Item
Prodotti consigliati
Origine biologica
rabbit
Coniugato
TRITC conjugate
Forma dell’anticorpo
IgG fraction of antiserum
Tipo di anticorpo
secondary antibodies
Clone
polyclonal
Forma fisica
buffered aqueous solution
Condizioni di stoccaggio
protect from light
tecniche
direct immunofluorescence: 1:64
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200
Temperatura di conservazione
−20°C
modifica post-traduzionali bersaglio
unmodified
Descrizione generale
Immunoglobulins (Igs) belongs immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobulin has two heavy (H) and two light (L), held together by disulphide linkages. Each light comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. IgG is abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.
Specificità
Anti-Mouse IgG (whole molecule)-TRITC antibody is specific for mouse IgG.
Immunogeno
Normal mouse serum
Applicazioni
Anti-Mouse IgG (whole molecule)-TRITC antibody is suitable for use in direct immunofluorescence (1:64), immunohistochemistry (1:200 dilution in formalin-fixed, paraffin-embedded sections), Ouchterlony double diffusion and electrophoresis techniques.
Azioni biochim/fisiol
Digestion of IgG by papain results in generation of fragment antigen binding (Fab) comprising one complete L chain and a variable and CH1 region of H chain. Pepsin digestion of IgG results in fragment crystallizable (fc), comprises the H chain constant region.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice .
Stato fisico
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
nwg
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Certificati d'analisi (COA)
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