SML0978

ML291

≥98% (HPLC)

• Sinonimo/i: CID52940465, N-(4-((4-Chloropiperidin-1-yl)sulfonyl)phenyl)-5-nitrofuran-2-carboxamide, SID134228465
• Formula empirica (notazione di Hill): C₁₆H₁₆ClN₃O₆S
• Numero CAS: 1523437-16-2
• Peso molecolare: 413.83
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C

Descrizione

Biochem/physiol Actions

ML291 specifically activates the apoptotic arm of the cellular unfolded protein response ( UPR) EC₅₀ = 762 nM) with 105-fold selectivity over activation of the adaptive UPR pathway. ML291 induces apoptosis in wild-type mouse embryonic fibroblasts (MEFs), but not in CHOP KO MEFs.

ML291 specifically activates the apoptotic arm of the cellular unfolded protein response.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable