SML0978

ML291

≥98% (HPLC)

• Sinonimo/i: CID52940465, N-(4-((4-Chloropiperidin-1-yl)sulfonyl)phenyl)-5-nitrofuran-2-carboxamide, SID134228465
• Formula empirica (notazione di Hill): C₁₆H₁₆ClN₃O₆S
• Numero CAS: 1523437-16-2
• Peso molecolare: 413.83
• Codice UNSPSC: 12352200
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Stato: powder
• Colore: white to beige
• Solubilità: DMSO: 20 mg/mL, clear
• Temperatura di conservazione: 2-8°C

Descrizione

Azioni biochim/fisiol

ML291 specifically activates the apoptotic arm of the cellular unfolded protein response ( UPR) EC₅₀ = 762 nM) with 105-fold selectivity over activation of the adaptive UPR pathway. ML291 induces apoptosis in wild-type mouse embryonic fibroblasts (MEFs), but not in CHOP KO MEFs.

ML291 specifically activates the apoptotic arm of the cellular unfolded protein response.

Caratteristiche e vantaggi

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Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable