SML0397

DR2313

≥98% (HPLC)

• Sinonimo/i: 3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
• Formula empirica (notazione di Hill): C₈H₁₀N₂OS
• Numero CAS: 284028-90-6
• Peso molecolare: 182.24
• NACRES: NA.77
• PubChem Substance ID: 329825393
• UNSPSC Code: 12352200
• MDL number: MFCD08703132
• Assay: ≥98% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: >2 mg/mL (warmed)
• storage temp.: 2-8°C
• SMILES string: CC1=NC(=O)C2=C(CCSC2)N1
• InChI: 1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
• InChI key: HRYKZAKEAVZGJD-UHFFFAOYSA-N

Descrizione

Biochem/physiol Actions

DR2313 is a PARP inhibitor.

DR2313 is a PARP-1; PARP-2 inhibitor (Ki = 0.23 mM). DR2313 has neuroprotective effects in both in vivo and in vitro ischemic models, and reduces cortical infarct volume in focal ischemia in rats.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable