S3322

Supercinnamaldehyde

≥98% (HPLC)

• Sinonimo/i: 1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one
• Formula empirica (notazione di Hill): C₁₂H₁₁NO₂
• Numero CAS: 70351-51-8
• Peso molecolare: 201.22
• NACRES: NA.77
• PubChem Substance ID: 329824530
• UNSPSC Code: 12352200
• MDL number: MFCD08530327
• Assay: ≥98% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: powder
• color: faintly red to very dark red
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CN1C(=O)C(=C\C(C)=O)\c2ccccc12
• InChI: 1S/C12H11NO2/c1-8(14)7-10-9-5-3-4-6-11(9)13(2)12(10)15/h3-7H,1-2H3/b10-7+
• InChI key: CZKBLHCEDVWPRN-JXMROGBWSA-N

Descrizione

Application

Supercinnamaldehyde may be used in transient receptor potential ankyrin 1 (TRPA 1)-mediated cell signaling studies.

Biochem/physiol Actions

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator. EC₅₀ = 0.8 μM.

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC₅₀ = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.

Disclaimer

Air-sensitive

Informazioni sulla sicurezza

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves