Phenyl-agarose is used in protein chromatography, affinity chromatography and hydrophobic interactions. Phenyl-agarose has been used to further the understanding of the digestive process of the pest species Dysdercus peruvianus as well as to study early onset dementia and Alzheimer′s disease.
Journal of neuroscience research, 88(1), 155-166 (2009-07-18)
The early-onset, irreversible, severe deficits of learning and memory in the senescence-accelerated mouse (SAM)-prone/8 (SAMP8) support its use as an animal model for human dementias of early onset. Possible implication of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) in cognitive dysfunction of
Clinical chemistry and laboratory medicine, 45(10), 1273-1276 (2007-08-01)
Presenilin 1 (PS1) and presenilin 2 (PS2) are membranous proteins involved in the pathology of Alzheimer's disease. The development of specific therapies targeted at PS1 or PS2 requires the determination of biochemical properties of presenilins. Hence, in this study we
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