P5155

D-Pantothenic acid hemicalcium salt

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

• Sinonimo/i: (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt, Calcium D-pantothenate, Vitamin B₅
• Formula condensata: HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca
• Numero CAS: 137-08-6
• Peso molecolare: 238.27
• Beilstein: 3769272
• Numero CE: 205-278-9
• Numero MDL: MFCD00002766
• Codice UNSPSC: 12352205
• eCl@ss: 34058012
• ID PubChem: 24898601
• NACRES: NA.75

Proprietà

• Origine biologica: synthetic (organic)
• Nome Commerciale: BioReagent
• Saggio: ≥98% (TLC)
• Stato: powder
• PM: M_w 238.27 g/mol
• tecniche: cell culture | insect: suitable; cell culture | mammalian: suitable; cell culture | plant: suitable
• Colore: white to off-white
• pH: 7.0-8 (25 °C, 50 g/L)
• Solubilità: water: soluble 50 mg/mL, clear, colorless
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
• InChI: 1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1; FAPWYRCQGJNNSJ-UBKPKTQASA-L

Descrizione

Descrizione generale

Plants and microorganisms, such as Escherichia coli are the major sources of D-pantothenic acid.[1] It is water soluble[2] and quite stable to heating.[3]

Applicazioni

D-Pantothenic acid hemicalcium salt has been used:

• as a component of FMX-turbodoma- derived media[2]
• as a supplement in DMEM (Dulbecco′s modified eagle media)/F-12 used for cell proliferation[4]
• as a supplement in preadipocyte media[5]

Precursor in the biosynthesis of coenzyme A.

Azioni biochim/fisiol

Along with coenzyme A (CoA, D-pantothenic acid is a precursor for acyl carrier protein.[1] These are essential cofactors[1] involved in fat, protein and carbohydrate metabolism. It also participates in the formation of acetylcholine neurotransmitter. D-pantothenic acid is considered as a source of nutrition and possesses immune function by mediating antibody formation. The production of cortisone is supported by D-pantothenic acid. It is essential for adrenal gland activity.[3]

Proprietà fisiche

Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)