Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
P2850
Phosphatase Inhibitor Cocktail 1
DMSO solution, mixture of inhibitors
Sinonimo/i:
Phosphatase Inhibitor
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Scegli un formato
1 ML
84,60 €
5 ML
389,00 €
Scegli un formato
Cambia visualizzazione
1 ML
84,60 €
5 ML
389,00 €
About This Item
Prodotti consigliati
Nome del prodotto
Phosphatase Inhibitor Cocktail 1, DMSO solution
Stato
DMSO solution
Livello qualitativo
Condizioni di spedizione
wet ice
Temperatura di conservazione
2-8°C
Descrizione generale
Phosphatase Inhibitor Cocktail 1 includes a mixture of inhibitors that will inhibit the L-isozymes of alkaline phosphatase as well as serine/threonine protein phosphatases such as PP1 and PP2A. This product contains microcystinLR, cantharidin, and (−)-p-bromotetramisole. Phosphatase Inhibitor Cocktail 1 has been replaced with P0044.
Applicazioni
Azioni biochim/fisiol
Phosphatases are active regulators of a number of important biological processes. Inhibition of phosphatases by small molecules is useful to study its biological role.[4]
Quantità
Recommended usage is a 100-fold dilution.
Risultati analitici
Tested on cell extracts from animal tissues such as bovine liver, human placenta, and rabbit muscle, as well as on extracts from A431 and Jurkat cell lines.
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
188.6 °F
Punto d’infiammabilità (°C)
87 °C
Scegli una delle versioni più recenti:
Certificati d'analisi (COA)
Lot/Batch Number
Non trovi la versione di tuo interesse?
Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I clienti hanno visto anche
Class III β-tubulin expression and in vitro resistance to microtubule targeting agents.
Stengel C, et al.
British Journal of Cancer, 102(2), 316-316 (2010)
Larger therapeutic window for steroid versus VEGF-A inhibitor in inflammatory angiogenesis: surprisingly similar impact on leukocyte infiltration.
Nakao S, et al.
Investigative Ophthalmology & Visual Science, 53(7), 3296-3302 (2012)
Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis.
Noren M A, et al.
Proceedings of the National Academy of Sciences of the USA, 103(28), 10606-10611 (2006)
X Zhao et al.
Mucosal immunology, 10(6), 1553-1568 (2017-04-13)
Virulent Mycobacterium tuberculosis (Mtb) triggers necrosis in host Mϕ, which is essential for successful pathogenesis in tuberculosis. Here we demonstrate that necrosis of Mtb-infected Mϕ is dependent on the action of the cytosolic Receptor Interacting Protein Kinase 3 (RIPK3) and
Aberrant Wnt/β-catenin signaling in pancreatic adenocarcinoma.
Zeng G, et al.
Neoplasia, 8(4), 279-289 (2006)
Articoli
The use of phosphatase inhibitors is critical for all types of phosphorylation studies. Compare phosphatase inhibitor cocktails to select the best one for your research.
-
What is the Department of Transportation shipping information for this product?
1 risposta-
Utile?
-
-
How stable is Product P2850, Phosphatase Inhibitor Cocktail 1? Can I freeze it?
1 risposta-
This reagent, as supplied and stored at 2-8°C, will be stable for four years from the date of manufacturing. Freezing is not recommended, because it may cause precipitation of the inhibitors.
Utile?
-
-
Product P2850, Phosphatase Inhibitor Cocktail 1, is solid when it arrived. Is it suitable to use?
1 risposta-
Since this solution is supplied in DMSO, it may solidify (melting point of DMSO is 16-19 deg C). Simply allow it to melt before use. This will not affect the product.
Utile?
-
-
What inhibitors are present in Product P2850, Phosphatase Inhibitor Cocktail 1, and in what concentrations?
1 risposta-
Cantharidin (Product Code C7632) inhibits protein phosphatase 2A (PP-2A). Bromotetramisole (Product Code B8132) inhibits alkaline phosphatases. Microcystin LR (Product Code M2912) inhibits protein phosphatases 1 and 2A (PP-1 and PP-2A). The concentrations of these inhibitors are considered proprietary.
Utile?
-
-
At what concentration should I use Product P2850, Phosphatase Inhibitor Cocktail 1?
1 risposta-
In most circumstannces, the product is used at a 100-fold dilution. This will inhibit the phosphatases in 5 mg of protein per mL of lysate.
Utile?
-
-
Is Product P2850, Phosphatase Inhibitor Cocktail 1, suitable for use on yeast?
1 risposta-
As far as we know, the phosphatases in mammalian cells also appear in yeast cells. Thus both cocktails, P5726 (Phosphatase cocktail II and P2850 (Phosphatase Inhibitor cocktail I), may be needed with yeast extracts.
Utile?
-
Filtri attivi
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.
