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Merck

P1925

Protein A–Agarose macrobeads

aqueous suspension

Sinonimo/i:

Protein A resin

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Informazioni su questo articolo

UNSPSC Code:
41106500
NACRES:
NA.56
MDL number:
Form:
aqueous suspension
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form

aqueous suspension

extent of labeling

~6 mg per mL

matrix activation

cyanogen bromide

matrix spacer

1 atom

capacity

~6 mg/mL binding capacity (human IgG)

storage temp.

2-8°C

Quality Level

General description

Protein A is an immunoglobulin (Ig)-binding protein that might be suitable for low-pressure antibody isolation. It is used to purify large amounts of IgG and binds to the Fc part of the antibody at the CH2–CH3 interface. Protein A-agarose is used for affinity chromatography, antibody purification and characterization, and protein A, G and L resins.

Application

Protein A–Agarose macrobeads has been used in immunoprecipitation. It has been used to study the effects of protein A immunoadsorption in patients with chronic dilated cardiomyopathy as well as to study multiple sclerosis and gastric cancer.

Physical form

Suspension in 0.9% NaCl containing 15Mm Sodium Azide

hcodes

Hazard Classifications

Aquatic Chronic 3

Classe di stoccaggio

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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B Blumbach et al.
Journal of cell science, 111 ( Pt 17), 2635-2644 (1998-08-14)
Porifera (sponges) are the oldest extant metazoan phylum. Dissociated sponge cells serve as a classic system to study processes of cell reaggregation. The reaggregation of dissociated cells is mediated by an extracellularly localized aggregation factor (AF), based on heterophilic interactions
C Wagner-Hülsmann et al.
Glycobiology, 6(8), 785-793 (1996-12-01)
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C Cullin et al.
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