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Merck
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P0880

Sigma-Aldrich

Pro-Gly

≥98% (TLC), suitable for cell culture

Sinonimo/i:

L-prolyl-glycine

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About This Item

Formula empirica (notazione di Hill):
C7H12N2O3
Numero CAS:
2578-57-6
Peso molecolare:
172.18
Numero MDL:
MFCD00022391
Codice UNSPSC:
12352202
ID PubChem:
24898135
NACRES:
NA.26

product name

Pro-Gly,

Saggio

≥98% (TLC)

Forma fisica

powder

tecniche

cell culture | mammalian: suitable

Colore

white

applicazioni

cell analysis

Temperatura di conservazione

−20°C

Stringa SMILE

OC(=O)CNC(=O)[C@@H]1CCCN1

InChI

1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1
RNKSNIBMTUYWSH-YFKPBYRVSA-N

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Categorie correlate

Azioni biochim/fisiol

PRO-GLY is a dipeptide that has previously been shown to prevent progression of diabetes.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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T A Gudasheva et al.
European journal of drug metabolism and pharmacokinetics, 22(3), 245-252 (1997-07-01)
The metabolism of a new piracetam analogue, the dipeptide cognitive enhancer N-phenylacetyl-L-prolylglycine ethyl ester (GVS-111) was studied in vivo. GVS-111 itself was not found in rat brain 1 h after 5 mg/kg i.p. administration up to limit of detection (LOD)
I P Ashmarin et al.
Biochemistry. Biokhimiia, 63(2), 119-124 (1998-06-02)
Our own data and data from the literature on the regulatory role of the simplest proline-containing peptides GP, PG, PGP, GPGG, and cyclic-PG are summarized. These peptides are involved in homeostasis of gastric mucosa and the anticoagulant and fibrinolytic potential
Shigeo Hayakawa et al.
Journal of the American Chemical Society, 129(25), 7936-7949 (2007-06-07)
We report a combined experimental and computational study of the proline effect in model dipeptides Pro-Gly and Gly-Pro. Gas-phase protonated peptide ions were discharged by glancing collisions with potassium or cesium atoms at 3 keV collision energies, and the peptide
Feng-Chun Wu et al.
The Journal of organic chemistry, 74(13), 4812-4818 (2009-05-23)
Tetrapeptides, containing a terminated primary amine and conformationally restricted D-Pro-Gly or D-Pro-Aib (2-aminoisobutanoic acid) segment as a strongly beta-turn-nucleating element, were designed and synthesized with condensation of N-module dipeptides with C-module dipeptides in solution. They were first applied to catalyze
A Hagting et al.
The Journal of biological chemistry, 269(15), 11391-11399 (1994-04-15)
Lactococcus lactis takes up di- and tripeptides via a proton motive force-dependent carrier protein. The gene (dtpT) encoding the di-tripeptide transport protein of L. lactis was cloned by complementation of a dipeptide transport-deficient and proline auxotrophic Escherichia coli strain. Functional
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