N6909

Neurturin human

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

• Sinonimo/i: NRTN, NTN
• Numero MDL: MFCD01867712
• Codice UNSPSC: 51111800

Proprietà

• Origine biologica: human
• Ricombinante: expressed in E. coli
• Saggio: >95% (SDS-PAGE)
• Stato: lyophilized powder
• Potenza: 15-50 ng/mL ED₅₀
• PM: monomer calculated mol wt ~12.5 kDa; predicted mol wt ~14 kDa by SDS-PAGE (reducing)
• Condizioni di stoccaggio: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• Impurezze: endotoxin, tested
• N° accesso UniProt: Q99748
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... NRTN(4902)

Descrizione

Azioni biochim/fisiol

Member of the glial cell line-derived neurotrophic factor family of ligands. Exerts potent effects on the function and survival of central and peripheral neurons. Activates the RET receptor tyrosine kinase, MAP kinase, and phosphatidylinositol 3-kinase pathways.

Member of the glial cell line-derived neurotrophic factor family of ligands. Exerts potent effects on the function and survival of central and peripheral neurons. Activates the RET receptor tyrosine kinase, MAP kinase, and phosphatidylinositol 3-kinase pathways. Human and mouse NTN share 91% sequence identity.

Stato fisico

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg bovine serum albumin.

Risultati analitici

The biological activity is measured by its ability to bind recombinant human GFRα2/Fc.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)