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M2172

Sigma-Aldrich

1-tioglicerolo

BioXtra, ≥97%

Sinonimo/i:

αα-monotioglicerolo, αα-tioglicerolo, 3-mercapto-1,2-propanediolo

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10 ML
133,00 €
50 ML
401,00 €
100 ML
459,90 €

133,00 €

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Cambia visualizzazione
10 ML
133,00 €
50 ML
401,00 €
100 ML
459,90 €

About This Item

Formula condensata:
HSCH2CH(OH)CH2OH
Numero CAS:
96-27-5
Peso molecolare:
108.16
Beilstein:
1732046
Numero CE:
202-495-0
Numero MDL:
MFCD00004879
Codice UNSPSC:
12352211
ID PubChem:
24896709
NACRES:
NA.25

133,00 €

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Nome Commerciale

BioXtra

Saggio

≥97%

Stato

liquid

Impurezze

≤0.0005% Phosphorus (P)

Residuo alla calcinazione

≤0.1%

Indice di rifrazione

n20/D 1.527 (lit.)

P. ebollizione

118 °C/5 mmHg (lit.)

Densità

1.25 g/mL at 25 °C (lit.)

Cationi in tracce

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

Temperatura di conservazione

2-8°C

Stringa SMILE

OCC(O)CS

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2
PJUIMOJAAPLTRJ-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

1-Thioglycerol stimulates the synthesis of porphyrin in aerobically growing Escherichia coli. It is an inhibitor of glycerol kinase activity in vitro and in situ. [1]

Applicazioni

It has been used in a study to assess thiol-sensitive genes and promoters of Escherichia coli. [2] [3]

Nota sulla preparazione

This product is miscible in ethanol (1 ml/ml, 50%, v/v), yielding a clear, colorless solution. It is also miscible in water (0.1 M).

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H302,H311 + H331,H315,H317

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

210.2 °F - closed cup

Punto d’infiammabilità (°C)

99 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
0000431413
0000431414
0000431414
0000431413
0000406286

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G T Javor et al.
Journal of bacteriology, 170(7), 3291-3293 (1988-07-01)
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive
W K Seltzer et al.
Life sciences, 39(16), 1417-1424 (1986-10-20)
The infantile form of glycerol kinase (GK) deficiency (McKusick No. 30703) (1) is characterized by adrenal cortical insufficiency, adrenal hypoplasia and developmental delay. The underlying biochemical mechanism(s) responsible for the observed clinical presentations are undetermined. Pursuant to our examination of
G T Javor
Journal of bacteriology, 171(10), 5607-5613 (1989-10-01)
The effect of 1-thioglycerol on the expression of genes of Escherichia coli was investigated. Pulse-labeled proteins from aerobically growing, 1-thioglycerol-treated E. coli were separated by two-dimensional gel electrophoresis, and their radioactivities were compared with those of identical proteins from nontreated
Nadja Franz et al.
Organic & biomolecular chemistry, 7(24), 5207-5218 (2009-12-22)
Hydrophilic/hydrophobic patterning is a powerful strategy to control folding in non-natural polymers/oligomers. In this contribution, we present a novel strategy for the preparation of alternating hydrophilic/hydrophobic patterned non-natural peptide foldamers. This strategy relies on the post-modification of a reactive peptide
Doron Burshtain et al.
Physical chemistry chemical physics : PCCP, 8(1), 158-164 (2006-02-17)
The difference in the heterogeneous binding of Mg(2+), Ca(2+) and Sr(2+) ions by 1-thioglycerol (TG) and 1,4-dithiothreitol (DTT) spontaneously adsorbed monolayers on Au has been studied following the changes in the double layer capacity. A mathematical treatment, based on calculating
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Domande

1–3 di 3 domande  

  1. How does the storage temperature relate to shipping conditions?

    1 risposta

    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Utile?

  2. What is the Department of Transportation shipping information for this product?

    1 risposta

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Utile?

  3. What is the concentration of the 1-thioglycerol?

    1 risposta

    1. The liquid is not a solution of 1-thioglycerol in some solvent. Rather, it is a neat liquid (i.e., essentially pure 1-thioglycerol). Based on a density of 1.245 g/mL and a molecular weight of 108.2 g/mole, one can calculate an effective molarity of 11.5 M. This information may be found on the M1753 product information sheet.

      Utile?

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