M0567
Microsomes from Liver, Pooled
from human male
Sinonimo/i:
lab equipment accessory
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Cambia visualizzazione
| A voi/SKU | Disponibilità | Prezzo |
|---|---|---|
1 vial | Per informazioni sulla disponibilità, contatta il Servizio Clienti. | 461,00 € |
Informazioni su questo articolo
NACRES:
NA.54
UNSPSC Code:
12352204
Biological source:
human male
461,00 €
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Servizio Tecnico
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Permettici di aiutartibiological source
human male
Quality Segment
form
liquid
packaging
vial of ~10 mg
shipped in
dry ice
storage temp.
−70°C
Application
Microsomes from Liver, Pooled has been used:
- in the glucuronidation kinetics assay to test the effects of herbal extracts on glucuronidation process[1]
- as a human liver microsomes (HLM) matrix for testing metabolic stability of talazoparib using liquid chromatography-tandem mass spectrometry (LC–MS/MS)[2]
- to study the metabolization of enantiomeric peptide D3[3]
Biochem/physiol Actions
Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.
N-glucuronidation of various 1-substituted imidazoles was found to occur in human liver microsomes. [6]
Source of drug metabolizing enzymes, including cytochrome P-450.
1 of 1
Questo articolo | |||
|---|---|---|---|
| biological source human male | biological source human | biological source human female | biological source mouse (CD-1) |
| form liquid | form - | form liquid | form liquid |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
| storage temp. −70°C | storage temp. −70°C | storage temp. −70°C | storage temp. −70°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| packaging vial of ~10 mg | packaging vial of ~10 mg | packaging vial of ~10 mg | packaging vial of ~10 mg |
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Classe di stoccaggio
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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