F2802

Fluvoxamine maleate

Name: Fluvoxamine maleate
Brand: SIGMA

neuronal serotonin reuptake inhibitor, solid

Sinonimo/i:

(E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate

Slide 1 of 1

Autenticati per visualizzare i prezzi organizzativi e contrattuali.

Scegli un formato

Prezzi e disponibilità al momento non sono disponibili

Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₅H₂₁F₃N₂O₂ · C₄H₄O₄

Numero CAS:

61718-82-9

Peso molecolare:

434.41

UNSPSC Code:

12352116

PubChem Substance ID:

24278162

NACRES:

NA.77

MDL number:

MFCD00269809

Form:

solid

Quality level:

200

Documenti fondamentali

Visualizza tutta la documentazione

Vai a

Servizio Tecnico

Hai bisogno di aiuto? Il nostro team di scienziati qualificati è a tua disposizione.

Permettici di aiutarti

Nome del prodotto

Fluvoxamine maleate, solid

form

solid

Quality Level

200

solubility

H₂O: soluble

originator

Solvay

storage temp.

2-8°C

SMILES string

COCCCC/C(C1=CC=C(C(F)(F)F)C=C1)=N\OCCN.OC(/C=C\C(O)=O)=O

InChI

1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1-

InChI key

LFMYNZPAVPMEGP-PIDGMYBPSA-N

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363), SLC6A4(6532)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Categorie correlate

Bioactive Small Molecule Inhibitors

Bioactive Small Molecules

Confronta articoli simili

Visualizza il confronto per intero

Mostra le differenze

1 of 4

Questo articolo	PHR1793	F-040	BP600
Sigma-Aldrich F2802 Fluvoxamine maleate	Supelco PHR1793 Fluvoxamine Maleate	Supelco F-040 Fluvoxamine maleate	BP600 Fluvoxamine maleate
form solid	form solid	form liquid	form solid
Quality Level 200	Quality Level 300	Quality Level 300	Quality Level -
storage temp. 2-8°C	storage temp. 2-30°C	storage temp. −20°C	storage temp. 2-8°C
solubility H₂O: soluble	solubility -	solubility -	solubility -
originator Solvay	originator -	originator -	originator -
Gene Information human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363), SLC6A4(6532)	Gene Information human ... SLC6A4(6532)	Gene Information human ... SLC6A4(6532)	Gene Information human ... SLC6A4(6532)

Application

Fluvoxamine maleate has been used as a test compound to determine the solubility and effective blood-brain barrier permeability.(2)

Biochem/physiol Actions

Fluvoxamine maleate is a selective neuronal serotonin reuptake inhibitor. It functions as an antidepressant and anti-obsessive agent. It is useful in treating obsessive compulsive disorder and panic disorder.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Solvay. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

0000472208

0000468273

0000468272

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Mosby's Drug Reference for Health Professions null

Crucial interactions between selective serotonin uptake inhibitors and sigma-1 receptor in heart failure.

Md Shenuarin Bhuiyan et al.

Journal of pharmacological sciences, 121(3), 177-184 (2013-02-23)

Depression is associated with a substantial increase in the risk of developing heart failure and is independently associated with increased cardiovascular morbidity and mortality. Inversely, cardiovascular disease can lead to severe depression. Thus, therapy with selective serotonin reuptake inhibitors (SSRIs)

Memantine add-on in moderate to severe obsessive-compulsive disorder: randomized double-blind placebo-controlled study.

Ali Ghaleiha et al.

Journal of psychiatric research, 47(2), 175-180 (2012-10-16)

There is a growing body of evidence for the efficacy of memantine augmentation in patients with obsessive-compulsive disorder (OCD). However, to date, no double-blind study has addressed this issue. The objective of the present randomized double-blind placebo-controlled study was to

Acute and sustained effects of a metabotropic glutamate 5 receptor antagonist in the novelty-suppressed feeding test.

Michihiko Iijima et al.

Behavioural brain research, 235(2), 287-292 (2012-08-28)

Accumulated evidence indicates that metabotropic glutamate 5 (mGlu5) receptor blockade exerts antidepressant-like and anxiolytic-like effects in several animal models. The novelty-suppressed feeding (NSF) test is used to measure anxiety-induced hypophagia in rodents. Anxiogenic-like behavior can be counteracted by acute treatment

A preliminary study of fluvoxamine maleate on depressive state and serum melatonin levels in patients after cerebral infarction.

Eiko Sunami et al.

Internal medicine (Tokyo, Japan), 51(10), 1187-1193 (2012-06-13)

Antidepressants have been recommended for the treatment of post-stroke depression (PSD). The purpose of this study was to evaluate the effect of fluvoxamine maleate, a selective serotonin re-uptake inhibitor (SSRI), on depressive state, sleep disturbance, and serum melatonin levels in

Visualizza tutti i documenti correlati

Articoli

Discover Bioactive Small Molecules for ADME/Tox

Contenuto correlato

Reboxetine mesylate-A selective norepinephrine reuptake inhibitor (SNRI)

Numero articolo commerciale globale

SKU	GTIN
F2802-10MG	04061833613320
F2802-50MG	04061832082073

Domande

Recensioni

Nessuna valutazione

Filtri attivi

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica