E8375

Eserine

• Sinonimo/i: Physostigmine
• Formula empirica (notazione di Hill): C₁₅H₂₁N₃O₂
• Numero CAS: 57-47-6
• Peso molecolare: 275.35
• EC Number: 200-332-8
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277867
• Beilstein/REAXYS Number: 91230
• MDL number: MFCD00151090

Proprietà

• assay: ≥99% (HPLC)
• mp: 102-104 °C (lit.)
• SMILES string: [H][C@]12N(C)CC[C@@]1(C)c3cc(OC(=O)NC)ccc3N2C
• InChI: 1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1
• InChI key: PIJVFDBKTWXHHD-HIFRSBDPSA-N
• Gene Information: human ... ACHE(43), APP(351), BCHE(590) ; mouse ... Ache(11423), Bche(12038), Chrm1(12669) ; rat ... Ache(83817), Bche(65036), Chrm2(81645)

Descrizione

Biochem/physiol Actions

Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.

Acetylcholinesterase inhibitor that crosses the blood-brain barrier.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) and Acetylcholine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Informazioni sulla sicurezza

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H330
• pcodes: P301 + P310 + P330 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Classe di stoccaggio: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges