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E5757

Sigma-Aldrich

Methionine Enkephalin-Arg-Phe acetate salt hydrate

≥97% (HPLC)

Sinonimo/i:

MERF, Tyr-Gly-Gly-Phe-Met-Arg-Phe

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About This Item

Formula empirica (notazione di Hill):
C42H56N10O9S · xC2H4O2 · yH2O
Peso molecolare:
877.02 (anhydrous free base basis)
Numero MDL:
MFCD11044450
Codice UNSPSC:
12352209
ID PubChem:
329798997
NACRES:
NA.32

Livello qualitativo

200

Saggio

≥97% (HPLC)

Temperatura di conservazione

−20°C

Stringa SMILE

O.CC(O)=O.CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc3ccccc3)C(O)=O

InChI

1S/C42H56N10O9S.C2H4O2.H2O/c1-62-20-18-32(39(58)50-31(13-8-19-46-42(44)45)38(57)52-34(41(60)61)23-27-11-6-3-7-12-27)51-40(59)33(22-26-9-4-2-5-10-26)49-36(55)25-47-35(54)24-48-37(56)30(43)21-28-14-16-29(53)17-15-28;1-2(3)4;/h2-7,9-12,14-17,30-34,53H,8,13,18-25,43H2,1H3,(H,47,54)(H,48,56)(H,49,55)(H,50,58)(H,51,59)(H,52,57)(H,60,61)(H4,44,45,46);1H3,(H,3,4);1H2/t30-,31-,32-,33-,34-;;/m0../s1
WOWLRTTTXHINBL-AVEXNAMASA-N

Azioni biochim/fisiol

Endogenous opioid heptapeptide that is an agonist at μ, δ, and κ receptors; also binds to σ2 receptors.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Charlotte R Feddersen et al.
BMC genomics, 20(1), 497-497 (2019-06-19)
The introduction of genome-wide shRNA and CRISPR libraries has facilitated cell-based screens to identify loss-of-function mutations associated with a phenotype of interest. Approaches to perform analogous gain-of-function screens are less common, although some reports have utilized arrayed viral expression libraries
Peter Densen et al.
Journal of immunology (Baltimore, Md. : 1950), 205(6), 1535-1539 (2020-08-10)
C8α-γ deficiency was examined in four unrelated African Americans. Two individuals were compound heterozygotes for a previously reported point mutation in exon 9. mRNA from the remaining six C8A alleles contained a 10 nt insertion between nt 992 and 993
David L Phillips et al.
Cornea, 34(11), 1383-1386 (2015-09-24)
To evaluate the outcome of the Boston type 1 keratoprosthesis (KPro-1) in eyes with iridocorneal endothelial syndromes and failed keratoplasties. A retrospective review was performed of every eye with a history of iridocorneal endothelial syndrome and a failed corneal transplant
Mohideen Abdul Kader et al.
Ophthalmic genetics, 38(3), 222-225 (2016-06-30)
To both characterize the clinical features of large primary open angle glaucoma (POAG) pedigree from a village in southern India and to investigate the genetic basis of their disease. Eighty-four members of a large pedigree received complete eye examinations including
Amadou Guindo et al.
Parasites & vectors, 14(1), 82-82 (2021-01-30)
Since the late 1990s, malaria control programmes have relied extensively on mass bednet distribution and indoor residual spraying. Both interventions use pesticides and target mosquitoes coming indoors either to feed or to rest. Unfortunately, these intensified vector control campaigns have
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