D7071

Dapoxetine hydrochloride

≥98% (HPLC)

• Sinonimo/i: (S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride, S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride, LY-210448 hydrochloride
• Formula empirica (notazione di Hill): C₂₁H₂₃NO · HCl
• Numero CAS: 129938-20-1
• Peso molecolare: 341.87
• Numero MDL: MFCD08272809
• Codice UNSPSC: 12352200
• ID PubChem: 329798842
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Stato: powder
• Attività ottica: [α]/D +125 to +135°, c = 1 in methanol
• Condizioni di stoccaggio: desiccated
• Colore: white
• Solubilità: DMSO: ≥20 mg/mL
• Ideatore: Eli Lilly
• Temperatura di conservazione: room temp
• Stringa SMILE: Cl.CN(C)[C@@H](CCOc1cccc2ccccc12)c3ccccc3
• InChI: 1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1; IHWDIQRWYNMKFM-BDQAORGHSA-N
• Informazioni sul gene: human ... SLC6A4(6532)

Descrizione

Descrizione generale

Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine.[1]

Azioni biochim/fisiol

Dapoxetine is capable of blocking recombinant Kv4.3 potassium voltage-gated channels. It is considered as safe.[1]

Potent Selective serotonin reuptake inhibitor (SSRI); used in treatment of premature ejaculation

Potent and selective SSRI

Caratteristiche e vantaggi

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302,H319,H413
• Consigli di prudenza: P264 - P273 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Classi di pericolo: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Irrit. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable