C5108
Cathepsin G from human sputum
≥0.2 units/mg protein, salt-free, lyophilized powder
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About This Item
Prodotti consigliati
Origine biologica
human sputum
Forma fisica
salt-free, lyophilized powder
Attività specifica
≥0.2 units/mg protein
N° accesso UniProt
Condizioni di spedizione
wet ice
Temperatura di conservazione
2-8°C
Informazioni sul gene
human ... CTSG(1511)
Azioni biochim/fisiol
Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.
Codice della classe di stoccaggio
13 - Non Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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Dermatology (Basel, Switzerland), 224(4), 352-360 (2012-07-05)
Cathepsin G, a serine protease that is activated by ultraviolet (UV) radiation, increases matrix metalloproteinase-1 (MMP-1) expression in fibroblasts through fibronectin (Fn) fragmentation and promotes the conversion of proMMP-1 to active MMP-1. This study investigated whether [2-[3-[[(1-benzoyl-4-piperidinyl)methylamino]carbonyl]-2-naphthalenyl]-1-(1-naphthalenyl)-2-oxoethyl]-phosphonic acid (KPA), a
Journal of immunology (Baltimore, Md. : 1950), 188(9), 4476-4487 (2012-03-31)
The neutrophil serine proteases cathepsin G (CG) and neutrophil elastase (NE) are involved in immune-regulatory processes and exert antibacterial activity against various pathogens. To date, their role and their therapeutic potential in pulmonary host defense against mycobacterial infections are poorly
Journal of cancer research and clinical oncology, 145(2), 383-392 (2018-11-24)
Elastin is a signature protein of lungs. Increased elastin turnover driven by altered proteolytic activity is an important part of lung tumorigenesis. Elastin-derived fragments have been shown to be pro-tumorigenic, however, little is known regarding the biomarker potential of such
Traffic (Copenhagen, Denmark), 13(5), 745-757 (2012-01-31)
Rabankyrin-5 (Rank-5) has been implicated as an effector of the small GTPase Rab5 and plays an important role in macropinocytosis. We have now identified Rank-5 as an interaction partner for the recycling regulatory protein, Eps15 homology domain 1 (EHD1). We
FEMS immunology and medical microbiology, 66(3), 445-448 (2012-09-05)
Although the Streptococcus pneumoniae polysaccharide capsule is an important virulence factor, ~ 15% of carriage isolates are nonencapsulated. Nonencapsulated S. pneumoniae are a cause of mucosal infections. Recent studies have shown that neutrophils kill S. pneumoniae predominately through neutrophil proteases, such as elastase
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