C4615
Cloricromene
≥98% (HPLC), solid
Sinonimo/i:
8-Chloro-3-(2-diethylaminoethyl)-7-ethoxycarbonylmethoxy-4-methylcoumarin hydrochloride, AD6
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Informazioni su questo articolo
Formula empirica (notazione di Hill):
C20H26ClNO5 · HCl
Numero CAS:
Peso molecolare:
432.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Servizio Tecnico
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Permettici di aiutartiassay
≥98% (HPLC)
form
solid
color
white
mp
221-222.3 °C
solubility
DMSO: 17 mg/mL, H2O: insoluble
storage temp.
2-8°C
SMILES string
Cl[H].CCOC(=O)COc1ccc2C(C)=C(CCN(CC)CC)C(=O)Oc2c1Cl
InChI
1S/C20H26ClNO5.ClH/c1-5-22(6-2)11-10-15-13(4)14-8-9-16(26-12-17(23)25-7-3)18(21)19(14)27-20(15)24;/h8-9H,5-7,10-12H2,1-4H3;1H
InChI key
CCCZJRFQJNGCCU-UHFFFAOYSA-N
Biochem/physiol Actions
Antithrombotic coumarin derivative that inhibits platelet and leukocyte function and suppresses arachidonic acid liberation by interfering with PLA2 activation.
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G Calapai et al.
Naunyn-Schmiedeberg's archives of pharmacology, 351(2), 209-215 (1995-02-01)
The effects of different doses (0.25, 0.5, 1 and 2 mg/kg i.p.) of cloricromene, a coumarine derivative, have been investigated on brain malondialdehyde levels, brain edema, myeloperoxidase activity, survival, locomotor hyperactivity and hippocampal neuronal loss following transient cerebral ischemia induced
D Altavilla et al.
The American journal of physiology, 268(4 Pt 2), H1412-H1417 (1995-04-01)
Splanchnic arteries were clamped for 45 min to induce splanchnic artery occlusion (SAO) shock in anesthetized rats. Sham-operated animals were used as controls. Survival time, serum tumor necrosis factor-alpha (TNF-alpha), white blood cell (WBC) count, mean arterial blood pressure, myeloperoxidase
Liquefying Compounds by Forming Deep Eutectic Solvents: A Case Study for Organic Acids and Alcohols.
Dinis O Abranches et al.
The journal of physical chemistry. B, 124(20), 4174-4184 (2020-04-24)
The criterion to distinguish a simple eutectic mixture from a deep eutectic solvent (DES) lies in the deviations to thermodynamic ideality presented by the components in the system. In this work, the current knowledge of the molecular interactions in types
Numero articolo commerciale globale
| SKU | GTIN |
|---|---|
| C4615-25MG | 04061833269879 |
| C4615-5MG | 04061833269886 |