B7688

PiB

≥98% (HPLC)

• Formula empirica (notazione di Hill): C₂₂H₁₈N₂O₈
• Numero CAS: 64005-90-9
• Peso molecolare: 438.39
• NACRES: NA.77
• PubChem Substance ID: 329773301
• UNSPSC Code: 12352200
• MDL number: MFCD00333607
• Assay: ≥98% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to light brown
• solubility: DMSO: 1-2 mg/mL (warmed)
• storage temp.: 2-8°C
• SMILES string: O=C(C1=C2C(C3=CC=C24)=C(C(N(CC(OCC)=O)C3=O)=O)C=C1)N(CC(OCC)=O)C4=O
• InChI: 1S/C22H18N2O8/c1-3-31-15(25)9-23-19(27)11-5-7-13-18-14(8-6-12(17(11)18)20(23)28)22(30)24(21(13)29)10-16(26)32-4-2/h5-8H,3-4,9-10H2,1-2H3
• InChI key: WNKQGFNIIHNGQM-UHFFFAOYSA-N

Descrizione

Biochem/physiol Actions

PiB is a Pin-1 inhibitor.

PiB is an inhibitor of the peptidylprolyl isomerase Pin-1. Inhibition of Pin-1 leads to destabilization of the transcription factor Nanog, which is required for maintenance of embryonic stem cell cultures.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable