A5737

Cefotetan disodium

• Formula empirica (notazione di Hill): C₁₇H₁₅N₇Na₂O₈S₄
• Numero CAS: 74356-00-6
• Peso molecolare: 619.58
• UNSPSC Code: 51282206
• NACRES: NA.85

Proprietà

• form: powder
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: cell wall synthesis | interferes
• storage temp.: 2-8°C
• InChI: 1S/C17H17N7O8S4.2Na/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28;;/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30);;/q;2*+1/p-2/b12-6-;;/t13?,15-,17+;;/m1../s1
• InChI key: ZQQALMSFFARWPK-GLHLDKNHSA-L

Descrizione

Biochem/physiol Actions

Cefotetan (cefotan) is a second-generation cephalosporin that is active against some strains of β-lactamase producing bacteria. It shows anti-microbial activity against Gram-positive and Gram-negative bacteria; it is more efficacious against Gram-negative and anaerobic bacteria. Cefotetan binds to penicillin-binding proteins and disrupts the cell wall synthesis.

Cefotetan has good protein binding capacity due to its half-life of 3 to 4 hours. The presence of methylthiotetrazole (MTT) side chain helps to enhance its potential for hypoprothrombinemia and disulfiram reactions. It possesses high antimicrobial activity against gram-negative bacilli than cefoxitin.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable