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Merck
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Documenti

63493

Sigma-Aldrich

Hoechst 34580

Trihydrochloride salt, ≥98.0% (HPLC)

Sinonimo/i:

N,N-Dimethyl-4-[5-(4-methyl-1-piperazinyl)[2,5′-bi-1H-benzimidazol]-2′-yl]benzenamine trihydrochloride, HOE 34580

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About This Item

Formula empirica (notazione di Hill):
C27H29N7 · 3HCl
Numero CAS:
911004-45-0
Peso molecolare:
560.95
Codice UNSPSC:
12352108
ID PubChem:
329759866
NACRES:
NA.32

Saggio

≥98.0% (HPLC)

Qualità

Trihydrochloride salt

Solubilità

H2O: 1 mg/mL, clear, slightly yellow to deep greenish-yellow

Fluorescenza

λex 357 nm; λem 490 nm±10 nm in H2O (free dye)

Temperatura di conservazione

−20°C

Stringa SMILE

Cl.Cl.Cl.CN1CCN(CC1)c2ccc3nc([nH]c3c2)-c4ccc5nc([nH]c5c4)-c6ccc(cc6)N(C)C

InChI

1S/C27H29N7.3ClH/c1-32(2)20-7-4-18(5-8-20)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-9-21(17-25(23)31-27)34-14-12-33(3)13-15-34;;;/h4-11,16-17H,12-15H2,1-3H3,(H,28,30)(H,29,31);3*1H
IPMZLKUUQSFUTA-UHFFFAOYSA-N

Categorie correlate

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Leonie Rosenberger et al.
Scientific reports, 9(1), 663-663 (2019-01-27)
Recently, exosomes secreted by menstrual mesenchymal stem cells have been identified as inhibitory agents of tumor angiogenesis and modulators of the tumor cell secretome in prostate and breast cancer. However, their direct effect on endothelial cells and paracrine mediators have
Irena Roci et al.
Cell cycle (Georgetown, Tex.), 19(20), 2676-2684 (2020-10-06)
Proliferating cells must synthesize a wide variety of macromolecules while progressing through the cell cycle, but the coordination between cell cycle progression and cellular metabolism is still poorly understood. To identify metabolic processes that oscillate over the cell cycle, we
Eveline A C Goossens et al.
International journal of molecular sciences, 21(10) (2020-05-21)
Myostatin is a negative regulator of muscle cell growth and proliferation. Furthermore, myostatin directly affects the expression of 14q32 microRNAs by binding the 14q32 locus. Direct inhibition of 14q32 microRNA miR-495-3p decreased postinterventional restenosis via inhibition of both vascular smooth
Alwin de Jong et al.
Frontiers in cardiovascular medicine, 7, 604821-604821 (2021-02-16)
Background: Inflammatory stimuli induced by NF-kB drive atherosclerotic lesion formation. The epigenetic P300/CBP associated factor (PCAF) post-transcriptionally acetylates FoxP3, which is required for regulatory T-cell (Treg) differentiation and immune modulation. We hypothesize that PCAF deficiency affects atherosclerosis via regulation of
Koos Rooijers et al.
Nature biotechnology, 37(7), 766-772 (2019-06-19)
Protein-DNA interactions are critical to the regulation of gene expression, but it remains challenging to define how cell-to-cell heterogeneity in protein-DNA binding influences gene expression variability. Here we report a method for the simultaneous quantification of protein-DNA contacts by combining
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