358M-1

MUM1 (MRQ-8) Mouse Monoclonal Antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: MRQ-8, monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (358M-14); vial of 0.5 mL concentrate (358M-15); bottle of 1.0 mL predilute (358M-17); vial of 1.0 mL concentrate (358M-16); bottle of 7.0 mL predilute (358M-18)
• Produttore/marchio commerciale: Cell Marque^®
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• Isotipo: IgG1κ
• Controllo: B-cell chronic lymphocytic leukemia (B-CLL), plasma cell myeloma, tonsil
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: cytoplasmic, nuclear
• Informazioni sul gene: human ... PWWP3A(84939)

Descrizione

Descrizione generale

MUM1 (multiple myeloma oncogene-1)/IRF4 (interferon regulatory factor 4) is a 50 kDa protein encoded by MUM1 gene, and a member of the interferon regulatory factor family of transcription factors. MUM1/IRF4 is expressed in the nuclei of plasma cells and a small percentage of germinal center (GC) B-cells located in the “light zone”. This antibody stains MUM1 protein, which is expressed in a subset of B-cells in the light zone of the germinal center, plasma cells, activated T-cells, and a wide spectrum of related hematolymphoid neoplasms derived from these cells. Therefore, this antibody is useful for the subclassiffication of lymphoid malignancies and an excellent marker for Reed-Sternberg cells of classic Hodgkin disease in combination with anti-CD30.

Qualità

IVD

IVD

IVD

RUO

Linkage

MUM1 Positive Control Slides, Product No. 358S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

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Note legali

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany