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Merck

08520

Quin-2

suitable for fluorescence, ≥95% (HPLC)

Sinonimo/i:

2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N′,N′-tetraacetic acid tetrapotassium salt, 2-{[2-Bis-(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis-(carboxymethyl)aminoquinoline tetrapotassium salt, Glycine,N-[2-[[8-[bis(carboxymethyl)amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-(carboxymethyl)-,potassium salt (1:4), Quin 2, Tetrapotassium Salt, tetrapotassium 2-[[2-[[2-[bis(2-oxido-2-oxoethyl)amino]-5-methylphenoxy]methyl]-6-methoxyquinolin-8-yl]-(2-oxido-2-oxoethyl)amino]acetate

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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C26H23K4N3O10
Numero CAS:
Peso molecolare:
693.87
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Beilstein/REAXYS Number:
5374262

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Quality Level

assay

≥95% (HPLC)

solubility

H2O: 10 mg/mL

fluorescence

λex 332 nm; λem 493 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+

suitability

suitable for fluorescence

storage temp.

2-8°C

InChI

1S/C26H27N3O10.4K/c1-15-3-6-19(28(10-22(30)31)11-23(32)33)21(7-15)39-14-17-5-4-16-8-18(38-2)9-20(26(16)27-17)29(12-24(34)35)13-25(36)37;;;;/h3-9H,10-14H2,1-2H3,(H,30,31)(H,32,33)(H,34,35)(H,36,37);;;;/q;4*+1/p-4

InChI key

XAGUNWDMROKIFJ-UHFFFAOYSA-J

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Questo articolo
Q0501551826SML3525
Quin-2 suitable for fluorescence, ≥95% (HPLC)

Sigma-Aldrich

08520

Quin-2

V-9302 ≥98% (HPLC)

Sigma-Aldrich

SML3525

V-9302

suitability

suitable for fluorescence

suitability

-

suitability

-

suitability

-

fluorescence

λex 332 nm; λem 493 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+

fluorescence

-

fluorescence

λex 332 nm (high), λex 354 nm (low), λem 505 nm (high), λem 510 nm (low)

fluorescence

-

solubility

H2O: 10 mg/mL

solubility

1 M NaOH: 50 mg/mL, clear, yellow-green

solubility

water: 10 mg/mL

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-10 to -25°C

assay

≥95% (HPLC)

assay

≥95%

assay

≥95% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

Application

Quin-2 has been demonstrated to be an indicator of Zn2+-protein complexes .

Other Notes

A fluorescent highly selective Ca++ indicator exhibiting fast uptake and release of Ca++[1]; Calibration substance in the measurement of cytoplasmic free calcium[2]

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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R Y Tsien
Biochemistry, 19(11), 2396-2404 (1980-05-27)
A new family of high-affinity buffers and optical indicators for Ca2+ is rationally designed and synthesized. The parent compound is 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA), a relative of the well-known chelator EGTA [ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid] in which methylene links between
R Y Tsien et al.
The Journal of cell biology, 94(2), 325-334 (1982-08-01)
A new, fluorescent, highly selective Ca2+ indicator , "quin2", has been trapped inside intact mouse and pig lymphocytes, to measure and manipulate cytoplasmic free Ca2+ concentrations, [Ca2+]i. Quin2 is a tetracarboxylic acid which binds Ca2+ with 1:1 stoichiometry and an
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Little is known about the molecular mechanisms whereby the human blood fluke Schistosoma japonicum is able to survive in the host venous blood system. Protease inhibitors are likely released by the parasite enabling it to avoid attack by host proteolytic

Numero articolo commerciale globale

SKUGTIN
45935-250MG04061832343167
T73202-50ML04061837372551
T73202-5ML04061837711909
08520-50MG04061833276723

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