39405

4-(Dimethylamino)pyridine

purum, ≥98.0% (NT)

• Sinonimo/i: N,N-Dimethylpyridin-4-amine, DMAP
• Formula empirica (notazione di Hill): C₇H₁₀N₂
• Numero CAS: 1122-58-3
• Peso molecolare: 122.17
• UNSPSC Code: 12352005
• NACRES: NA.22
• PubChem Substance ID: 329755867
• EC Number: 214-353-5
• Beilstein/REAXYS Number: 110354
• MDL number: MFCD00006418
• Assay: ≥98.0% (NT)
• Form: crystals, pellets

Proprietà

• grade: purum
• Quality Segment: 200
• assay: ≥98.0% (NT)
• form: crystals, pellets
• mp: 108-110 °C (lit.), 111-114 °C
• solubility: methanol: 0.1 g/mL, clear, colorless to almost colorless
• functional group: amine
• SMILES string: CN(C)c1ccncc1
• InChI: 1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3
• InChI key: VHYFNPMBLIVWCW-UHFFFAOYSA-N

Descrizione

General description

4-(Dimethylamino)pyridine is generally employed as a catalyst in the acylation of amines, alcohols, enolates, and phenols. It can also be used in the esterification of carboxylic acids. It is known to exhibit good catalytic activity in non-polar solvents.

Application

4-(Dimethylamino)pyridine can be used:

• As a capping agent in the preparation of water-soluble gold nanoparticles.
• As an initiator in the polymerization of epoxy monomers.
• As an auxiliary reagent in the electroless preparation of gold nanotubes applicable in catalysis.[1]
• As a catalyst in the preparation of γ- and δ-lactones via iodolactonization of γ,δ-unsaturated carboxylic acids.

A highly efficient catalyst for acylation reactions

Other Notes

Hypernucleophilic acylation catalyst.

Informazioni sulla sicurezza

• pictograms: GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H301 + H331,H310,H315,H318,H370,H411
• pcodes: P262 - P273 - P280 - P301 + P310 - P302 + P352 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1
• target_organs: Nervous system
• Classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: 255.2 °F
• flash_point_c: 124 °C
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges