1.09334

LiChrosorb^® RP-18 (10 µm) HPLC Columns

HPLC sorbent

• Sinonimo/i: TM=["LiChrosorb"] C18 sorbent for HPLC
• UNSPSC Code: 41115709
• NACRES: SB.52
• Particle size: 10 μm
• Matrix active group: C18 (RP18), C18 bonding phase
• Pore size: 100 Å pore size
• Matrix: fully porous particle

Proprietà

• Nome del prodotto: LiChrosorb^® RP-18 (10 µm),
• material: stainless steel column
• agency: suitable for USP L1
• product line: LiChrosorb^®
• feature: endcapped: no
• parameter: 60 °C max. temp.
• technique(s): HPLC: suitable, mass spectrometry (MS): suitable (Low)
• matrix: fully porous particle
• matrix active group: C18 (RP18), C18 bonding phase
• particle size: 10 μm
• pore size: 100 Å pore size
• operating pH range: 2-7.5
• bulk density: 200‑400 kg/m³
• separation technique: reversed phase
• storage temp.: no temp limit

Descrizione

Application

• High-performance liquid chromatographic determination of the antifungal drug fluconazole in plasma and saliva of human immunodeficiency virus-infected patients.: This study highlights a method using RP-18 for the determination of fluconazole, demonstrating the column′s effectiveness in bioanalytical contexts (Beijnen JH et al., 1995).


• Determination of serum aluminium using an ion-pair reversed-phase high-performance liquid chromatographic-fluorimetric system with lumogallion.: This research utilizes RP-18 to analyze serum aluminum, showcasing its utility in trace metal analysis in clinical samples (Ong CN et al., 1995).


• A radiochemical high-performance liquid chromatographic method for the analysis of 2-fluoro-2-deoxy-D-glucose-derived metabolites in human chondrocytes.: The method developed employs RP-18, underscoring its role in the radiochemical analysis of complex biological matrices (Greiling H et al., 1993).


• Systematic approach to the determination of cephalosporins in biological fluids by reversed-phase liquid chromatography.: This study demonstrates the application of RP-18 in the pharmacokinetic analysis of cephalosporins, further proving the column′s broad applicability in pharmaceutical analyses (Juge F et al., 1983).


• Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high-performance liquid chromatography with electrochemical detection.: This research uses RP-18 to simultaneously quantify multiple neurotransmitters, highlighting its sensitivity and specificity for neurochemical analysis (Huot S et al., 1982).

Analysis Note

Theoretical Plates (N/m) (Toluene): ≥ 25000
stability testing (performance): passes test
particle size (Malvern) (d10): 8.7 - 10.0 µm
particle size (Malvern) (d50): 12.0 - 14.0 µm
particle size (Malvern) (d90): 17.5 - 20.5 µm

Legal Information

LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable