1.04239

Glutaraldeide

for electron microscopy

• Sinonimo/i: Dialdeide glutarica, Pentano-1,5-diale
• Formula condensata: OHC(CH₂)₃CHO
• Numero CAS: 111-30-8
• Peso molecolare: 100.12
• NACRES: NA.21
• UNSPSC Code: 12352114
• Beilstein/REAXYS Number: 605390
• MDL number: MFCD00007025
• Technique(s): electron microscopy: suitable
• Bp: 100.5 °C/1013 hPa
• Vapor pressure: 0.27 hPa ( 20 °C)

Proprietà

• vapor pressure: 0.27 hPa ( 20 °C)
• Quality Segment: 200
• form: liquid
• concentration: 23.5-26.5% (alkalimetric)
• technique(s): electron microscopy: suitable
• color: colorless
• pH: >3.0 (20 °C in H₂O)
• bp: 100.5 °C/1013 hPa
• mp: -6 °C
• density: 1.06 g/cm³ at 20 °C
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: 2-8°C
• SMILES string: [H]C(CCCC([H])=O)=O
• InChI: 1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
• InChI key: SXRSQZLOMIGNAQ-UHFFFAOYSA-N

Descrizione

General description

Glutardialdehyde solution 25% - for electron microscopy, is a fixing agent for specimens destined for morphological and enzyme histochemical analysis. The 25% Glutardialdehyde solution is used for the fixation of specimen of human origin for semi-thin cuttings and electron microscopy. It is diluted with phosphate buffer(Potassium dihydrogen phosphate for analysis EMSURE^® ISO (Product number 1.04873) or di-Sodium hydrogen phosphate anhydrous for analysis EMSURE^® ACS,Reag. Ph Eur (Product number 1.06586)
to achieve the corresponding working concentration. Alternatively, especially sensitive material used for enzyme histochemistry, will be fixed with glutardialdehyde according to P.J. Anderson, purified and filled into ampoules under nitrogen (Product number 1.12179). Sensitive enzymes e.g. endogenous peroxidase can often only be visualized in this way. It is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Analysis Note

Assay (alkalimetric): 23.5 - 26.5 %
pH-value: ≥ 3.0
Density (d 20 °C/ 4 °C): 1.060 - 1.065
Absorbance A (235 nm; 1:200 deluted with water; 1 cm): ≤ 0.3

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Parola di avvertenza: Danger
• Avvertenze di sicurezza: P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• Organi bersaglio: Respiratory system
• supp_hazards: EUH071
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable
• Pittogrammi: GHS08,GHS05,GHS07,GHS09
• Codici di pericolo: H302 + H332,H314,H317,H334,H335,H410
• Classe di stoccaggio: 8A - Combustible corrosive hazardous materials