TOP1
topoisomerase (DNA) I
Sinonimi:
TOPI
Specie:
Human TOP1 (7150), Mouse Top1 (21969), Rat Top1 (64550), domestic cat TOP1 (101093174), naked mole-rat Top1 (101704241), domestic guinea pig Top1 (100716716), sheep TOP1 (101103086), cow TOP1 (534799), dog TOP1 (477229), chicken TOP1 (396004) ...Più
ID UniProtKB:
ID gene:
- Human(7150) Summary: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]
- Mouse(21969) topoisomerase (DNA) I
- Rat(64550) topoisomerase (DNA) I
- domestic cat(101093174) topoisomerase (DNA) I
- naked mole-rat(101704241) topoisomerase (DNA) I
- domestic guinea pig(100716716) topoisomerase (DNA) I
- sheep(101103086) topoisomerase (DNA) I
- cow(534799) topoisomerase (DNA) I
- dog(477229) topoisomerase (DNA) I
- chicken(396004) topoisomerase (DNA) I
- fruit fly(32458) Topoisomerase 1
- Zebrafish(327179) topoisomerase (DNA) I
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anticorpo anti-complessi covalenti topoisomerasi I/DNA, clone 1.1A, clone 1.1A, from mouse,
Reattività con
human, mouse
Applicazione
ELISA
dot blot
flow cytometry
immunocytochemistry
dot blot
flow cytometry
immunocytochemistry
Monoclonal Anti-Topoisomerase I antibody produced in mouse, clone Mab1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
microarray
western blot
western blot
Anti-TOP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-DNA topoisomerase I (TOP1) Antibody, clone 3D4W6, Rabbit Monoclonal, ,
Reattività con
human, rat
Applicazione
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Monoclonal Anti-TOP1 antibody produced in mouse, clone 1A1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
N° Catalogo
Descrizione
Specie
Topo I (197-651) (core domain) human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Specie
human
Topo I (N1-197) (NTD) human, recombinant, expressed in insect cells, ≥85% (SDS-PAGE),
Specie
human
Topo I (C651-765) (C terminal domain) human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Specie
human
Topo I (Y723F) (mt Y723F) human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Specie
human